Literature DB >> 24485045

Optimizing bioluminescence imaging to study protozoan parasite infections.

Martin C Taylor1, John M Kelly2.   

Abstract

Bioluminescence imaging is a non-invasive technique which can be used to monitor infections in real-time. However, its utility is restricted by difficulties in detecting pathogens in deep tissue. 'Red-shifted' luciferases, which emit light of longer wavelength than standard bioluminescence-generating proteins, greatly enhance sensitivity, and have wide applicability for studying parasite infections.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  bioluminescence; in vivo imaging; red-shifted luciferase; trypanosomes

Mesh：

Substances：

Year:  2014        PMID： 24485045     DOI： 10.1016/j.pt.2014.01.006

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN： 1471-4922


  5 in total

1.  An enhanced chimeric firefly luciferase-inspired enzyme for ATP detection and bioluminescence reporter and imaging applications.

Authors:  Bruce R Branchini; Tara L Southworth; Danielle M Fontaine; Dawn Kohrt; Munya Talukder; Elisa Michelini; Luca Cevenini; Aldo Roda; Martha J Grossel
Journal:  Anal Biochem       Date:  2015-06-04       Impact factor: 3.365

2.  Red-emitting chimeric firefly luciferase for in vivo imaging in low ATP cellular environments.

Authors:  Bruce R Branchini; Tara L Southworth; Danielle M Fontaine; Dawn Kohrt; Franceine S Welcome; Catherine M Florentine; Emma R Henricks; Demetria B DeBartolo; Elisa Michelini; Luca Cevenini; Aldo Roda; Martha J Grossel
Journal:  Anal Biochem       Date:  2017-07-04       Impact factor: 3.365

Review 3.  A new experimental model for assessing drug efficacy against Trypanosoma cruzi infection based on highly sensitive in vivo imaging.

Authors:  Michael D Lewis; Amanda Fortes Francisco; Martin C Taylor; John M Kelly
Journal:  J Biomol Screen       Date:  2014-10-08

Review 4.  Chemiluminescence and Bioluminescence Imaging for Biosensing and Therapy: In Vitro and In Vivo Perspectives.

Authors:  Yongcun Yan; Pengfei Shi; Weiling Song; Sai Bi
Journal:  Theranostics       Date:  2019-05-31       Impact factor: 11.556

5.  Multicolor bioluminescence boosts malaria research: quantitative dual-color assay and single-cell imaging in Plasmodium falciparum parasites.

Authors:  Luca Cevenini; Grazia Camarda; Elisa Michelini; Giulia Siciliano; Maria Maddalena Calabretta; Roberta Bona; T R Santha Kumar; Andrea Cara; Bruce R Branchini; David A Fidock; Aldo Roda; Pietro Alano
Journal:  Anal Chem       Date:  2014-08-15       Impact factor: 6.986
  5 in total

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