| Literature DB >> 24482183 |
Lianping Xing1, Brendan F Boyce1.
Abstract
Osteoclasts are the only cell type in the body to resorb bone. Osteoclasts play a critical role in physiologic and pathologic bone remodeling. Many genetic mouse models affect the skeleton by regulating osteoclast function directly or indirectly. This protocol describes a procedure for generating osteoclasts from mouse bone marrow cells using macrophage colony stimulating factor and receptor activator of NF-κB ligand.Entities:
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Year: 2014 PMID： 24482183 DOI： 10.1007/978-1-62703-989-5_23
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745