Literature DB >> 24482119

Nickel-catalyzed C-H alkylations: direct secondary alkylations and trifluoroethylations of arenes.

Weifeng Song1, Sebastian Lackner, Lutz Ackermann.   

Abstract

A versatile nickel catalyst allowed for C-H alkylations of unactivated arenes with challenging secondary alkyl bromides and chlorides. The high catalytic efficacy also set the stage for direct secondary alkylations of indoles as well as C-H trifluoroethylations with ample substrate scope.
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  CH activation; auxiliary assistance; nickel; secondary alkylation; trifluoroethylation

Year:  2014        PMID： 24482119     DOI： 10.1002/anie.201309584

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  23 in total

1.  Ligand-Enabled Meta-C-H Alkylation and Arylation Using a Modified Norbornene.

Authors:  Peng-Xiang Shen; Xiao-Chen Wang; Peng Wang; Ru-Yi Zhu; Jin-Quan Yu
Journal:  J Am Chem Soc       Date:  2015-09-03       Impact factor: 15.419

2.  Cobalt-catalyzed, aminoquinoline-directed C(sp²)-H bond alkenylation by alkynes.

Authors:  Liene Grigorjeva; Olafs Daugulis
Journal:  Angew Chem Int Ed Engl       Date:  2014-07-24       Impact factor: 15.336

3.  Bidentate, monoanionic auxiliary-directed functionalization of carbon-hydrogen bonds.

Authors:  Olafs Daugulis; James Roane; Ly Dieu Tran
Journal:  Acc Chem Res       Date:  2015-03-10       Impact factor: 22.384

4.  Cobalt-promoted dimerization of aminoquinoline benzamides.

Authors:  Liene Grigorjeva; Olafs Daugulis
Journal:  Org Lett       Date:  2015-02-17       Impact factor: 6.005

5.  Palladium-catalyzed, ring-forming aromatic C-H alkylations with unactivated alkyl halides.

Authors:  Alexander R O Venning; Patrick T Bohan; Erik J Alexanian
Journal:  J Am Chem Soc       Date:  2015-03-16       Impact factor: 15.419

6.  Nickel-catalyzed, ring-forming aromatic C-H alkylations with unactivated alkyl halides.

Authors:  Quentin D Tercenio; Erik J Alexanian
Journal:  Tetrahedron       Date:  2019-05-25       Impact factor: 2.457

7.  Palladium-catalyzed intramolecular C-H difluoroalkylation: synthesis of substituted 3,3-difluoro-2-oxindoles.

Authors:  Shi-Liang Shi; Stephen L Buchwald
Journal:  Angew Chem Int Ed Engl       Date:  2014-12-04       Impact factor: 15.336

8.  Cobalt-catalyzed direct carbonylation of aminoquinoline benzamides.

Authors:  Liene Grigorjeva; Olafs Daugulis
Journal:  Org Lett       Date:  2014-08-22       Impact factor: 6.005

9.  Cobalt-catalyzed, aminoquinoline-directed coupling of sp(2) C-H bonds with alkenes.

Authors:  Liene Grigorjeva; Olafs Daugulis
Journal:  Org Lett       Date:  2014-08-22       Impact factor: 6.005

10.  Ligand-promoted alkylation of C(sp3)-H and C(sp2)-H bonds.

Authors:  Ru-Yi Zhu; Jian He; Xiao-Chen Wang; Jin-Quan Yu
Journal:  J Am Chem Soc       Date:  2014-09-15       Impact factor: 15.419
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.