BACKGROUND: Previous research in cardiac patients suggested that type D personality, defined as a combination of negative affectivity (NA) and social inhibition (SI), was associated with adverse outcome. PURPOSE: The objective of this prospective study was to examine the independent prognostic value of type D in patients with coronary artery disease (CAD). METHODS: A total of 465 patients completed the Type D Scale (DS14) questionnaire before undergoing stent implantation and were followed up for 5 years. RESULTS: In a Cox regression model adjusted for selected confounders, we found a trend towards NA for the prediction of nonfatal major adverse cardiovascular event (MACE, hazard ratio (HR) = 1.07, 95 % confidence intervals (CIs) = 0.99-1.14, p = 0.074), while, in contrast, SI was a significant and independent predictor of better outcome (HR = 0.92, 95 % CI = 0.86-0.99, p = 0.027). CONCLUSIONS: In a cohort of CAD patients, the type D pattern was not linked to adverse outcome, whereas SI was negatively associated with MACE.
BACKGROUND: Previous research in cardiac patients suggested that type D personality, defined as a combination of negative affectivity (NA) and social inhibition (SI), was associated with adverse outcome. PURPOSE: The objective of this prospective study was to examine the independent prognostic value of type D in patients with coronary artery disease (CAD). METHODS: A total of 465 patients completed the Type D Scale (DS14) questionnaire before undergoing stent implantation and were followed up for 5 years. RESULTS: In a Cox regression model adjusted for selected confounders, we found a trend towards NA for the prediction of nonfatal major adverse cardiovascular event (MACE, hazard ratio (HR) = 1.07, 95 % confidence intervals (CIs) = 0.99-1.14, p = 0.074), while, in contrast, SI was a significant and independent predictor of better outcome (HR = 0.92, 95 % CI = 0.86-0.99, p = 0.027). CONCLUSIONS: In a cohort of CAD patients, the type D pattern was not linked to adverse outcome, whereas SI was negatively associated with MACE.
Authors: Johan S Bundgaard; Lauge Østergaard; Gunnar Gislason; Jens J Thune; Jens C Nielsen; Jens Haarbo; Lars Videbæk; Line L Olesen; Anna M Thøgersen; Christian Torp-Pedersen; Susanne S Pedersen; Lars Køber; Ulrik M Mogensen Journal: Qual Life Res Date: 2019-07-10 Impact factor: 4.147