| Literature DB >> 24481530 |
Abstract
DNA methylation is a fundamental epigenetic mechanism governing regulation of gene expression during mammalian development. A recent study published in Nature shows a novel long noncoding RNA (lncRNA) arising from the CEBPA gene locus (termed ecCEBPA) that is critical for regulation of DNA methylation at this site through the association of ecCEBPA with DNA methyltransferase 1, DNMT1.Entities:
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Year: 2014 PMID: 24481530 PMCID: PMC3945889 DOI: 10.1038/cr.2014.13
Source DB: PubMed Journal: Cell Res ISSN: 1001-0602 Impact factor: 25.617