Literature DB >> 24481054

Enantioselective hydroacylation of N-vinylindole-2-carboxaldehydes.

Avipsa Ghosh1, Levi M Stanley.   

Abstract

We report catalytic, enantioselective intramolecular hydroacylation of N-vinylindole-2-carboxaldehydes. These hydroacylation reactions occur in the presence of a readily accessible rhodium catalyst and form chiral, non-racemic 2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-ones in high yields with excellent enantioselectivities.

Entities:  

Year:  2014        PMID: 24481054     DOI: 10.1039/c4cc00210e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  6 in total

1.  Enantioselective hydroacylation of olefins with rhodium catalysts.

Authors:  Stephen K Murphy; Vy M Dong
Journal:  Chem Commun (Camb)       Date:  2014-11-18       Impact factor: 6.222

2.  Catalytic Cycloisomerization onto a Carbonyl Oxygen.

Authors:  Shicheng Shi; Jonathan L Kuo; Tao Chen; Jack R Norton
Journal:  Org Lett       Date:  2020-07-22       Impact factor: 6.005

3.  Mechanisms and reactivity differences for the cobalt-catalyzed enantioselective intramolecular hydroacylation of ketones and alkenes: insights from density functional calculations.

Authors:  Qingxi Meng; Fen Wang
Journal:  J Mol Model       Date:  2016-02-18       Impact factor: 1.810

4.  Enantioselective synthesis of polycyclic nitrogen heterocycles by Rh-catalyzed alkene hydroacylation: constructing six-membered rings in the absence of chelation assistance.

Authors:  Xiang-Wei Du; Avipsa Ghosh; Levi M Stanley
Journal:  Org Lett       Date:  2014-07-14       Impact factor: 6.005

5.  Diverse saturated heterocycles from a hydroacylation/conjugate addition cascade.

Authors:  Ndidi U N Iwumene; Daniel F Moseley; Robert D C Pullin; Michael C Willis
Journal:  Chem Sci       Date:  2022-01-19       Impact factor: 9.825

6.  Rh-Catalyzed Desymmetrization of α-Quaternary Centers by Isomerization-Hydroacylation.

Authors:  Jung-Woo Park; Kevin G M Kou; Daniel K Kim; Vy M Dong
Journal:  Chem Sci       Date:  2015-06-12       Impact factor: 9.825

  6 in total

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