Literature DB >> 24480952

Multivariate analysis on risk factors for postoperative ileus after lateral lumbar interbody fusion.

Motasem A Al Maaieh1, Jerry Y Du, Alexander Aichmair, Russel C Huang, Alexander P Hughes, Frank P Cammisa, Federico P Girardi, Andrew A Sama.   

Abstract

STUDY
DESIGN: Retrospective cohort study.
OBJECTIVE: To assess for independent risk factors of postoperative ileus (POI) after lateral lumbar interbody fusion (LLIF). SUMMARY OF BACKGROUND DATA: POI is frequently observed in anterior lumbar interbody fusion due to significant bowel manipulation during the approach. LLIF is a minimally invasive approach to the anterior column with reduced bowel manipulation and surgical time. However, there is a paucity of literature on POI after LLIF.
METHODS: A retrospective review was performed of records of patients who underwent LLIF from January 2006 to December 2011 at a single institution. Patients with prolonged and recurrent POI were identified by review of hospital stay documentation by a fellowship-trained spine surgeon and a research fellow. POI patients were matched 1:1 to a control cohort without POI. Uni- and multivariate analyses were performed on demographic, comorbidity, surgical indication, medication, and perioperative details to identify independent risk factors for POI.
RESULTS: Incidence of prolonged or recurrent POI after LLIF was 7.0% (42/596). Postoperative length of stay was significantly higher for patients with POI (9.9 ± 4.3 d) than control patients (5.6 ± 4.1 d) (P < 0.001). The incidence of ileus in the first 100 LLIF cases (11%) was not significantly higher than in the last 100 LLIF cases (6%) (P = 0.21). Independent risk factors were history of gastroesophageal reflux disease (P < 0.01, adjusted odds ratio [aOR]: 24.31), posterior instrumentation (P = 0.002, aOR: 19.48), and LLIF at L1-L2 (P = 0.04, aOR: 7.82). A history of prior abdominal surgery approached significance as an independent protective factor (P = 0.07, aOR: 0.29).
CONCLUSION: There was a relatively high incidence of POI after LLIF. Independent risk factors for POI were a history of gastroesophageal reflux disease, posterior instrumentation, and LLIF at L1-L2. A history of prior abdominal surgery approached significance as an independent protective factor. LEVEL OF EVIDENCE: 3.

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Year:  2014        PMID: 24480952     DOI: 10.1097/BRS.0000000000000238

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


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