| Literature DB >> 24480436 |
Heli Venhoranta1, Shun Li2, Sylwia Salamon3, Tatiana Flisikowska2, Magnus Andersson1, Marek Switonski3, Alexander Kind2, Angelika Schnieke2, Krzysztof Flisikowski4.
Abstract
The existence of non-CpG methylation in mammalian DNA has mainly been observed in embryonic stem cells, but its functional significance is uncertain. We found an age-dependent non-CpG hypermethylation in DMR at the 3' end of the MIMT1 in the placenta of intrauterine growth restricted foetuses in cattle. Data suggest that this DMR play a role in epigenetic regulation of the PEG3 domain.Entities:
Keywords: Epigenetic regulation; Intrauterine growth restriction; Mammalian DNA; Non-CpG methylation; PEG3
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Year: 2014 PMID： 24480436 DOI： 10.1016/j.bbrc.2014.01.071
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575