Literature DB >> 2447843

Use of cultured epithelial cells, including keratinocytes, for the detection of antinuclear antibodies.

I Leigh1, F Wojnarowska, S Burge, B Bhogal, T Zhu.   

Abstract

The use of cultured human epithelial cells as a substrate for the detection of antinuclear antibodies (ANAs) improves the sensitivity of detection above the standard substrates used. Standard antisera have been screened against a series of epithelial cell lines, including keratinocytes. Selected cells have then been used to detect ANAs in 78 patients with discoid lupus erythematosus.

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Year:  1987        PMID: 2447843      PMCID: PMC1003425          DOI: 10.1136/ard.46.12.929

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN: 0003-4967            Impact factor:   19.103


  16 in total

1.  Autoantibody to a nuclear antigen in proliferating cells.

Authors:  K Miyachi; M J Fritzler; E M Tan
Journal:  J Immunol       Date:  1978-12       Impact factor: 5.422

Review 2.  Human breast carcinoma cells in continuous culture: a review.

Authors:  L W Engel; N A Young
Journal:  Cancer Res       Date:  1978-11       Impact factor: 12.701

3.  Indirect immunofluorescent antinuclear antibody tests: comparison of sensitivity and specificity of different substrates.

Authors:  J E Cleymaet; R M Nakamura
Journal:  Am J Clin Pathol       Date:  1972-10       Impact factor: 2.493

4.  The mesothelial keratins: a new family of cytoskeletal proteins identified in cultured mesothelial cells and nonkeratinizing epithelia.

Authors:  Y J Wu; L M Parker; N E Binder; M A Beckett; J H Sinard; C T Griffiths; J G Rheinwald
Journal:  Cell       Date:  1982-12       Impact factor: 41.582

5.  Antinuclear and anticytoplasmic antibodies. Concepts and misconceptions.

Authors:  R D Sontheimer; J S Deng; J N Gilliam
Journal:  J Am Acad Dermatol       Date:  1983-09       Impact factor: 11.527

6.  Standardization of the immunofluorescence test for autoantibody to nuclear antigens (ANA): use of reference sera of defined antibody specificity.

Authors:  D P Molden; R M Nakamura; E M Tan
Journal:  Am J Clin Pathol       Date:  1984-07       Impact factor: 2.493

7.  Circulating T- and B-cell abnormalities in cutaneous lupus erythematosus.

Authors:  P Kind; P E Lipsky; R D Sontheimer
Journal:  J Invest Dermatol       Date:  1986-03       Impact factor: 8.551

8.  Effects of SV40 transformation on the cytoskeleton and behavioural properties of human keratinocytes.

Authors:  J Taylor-Papadimitriou; P Purkis; E B Lane; I A McKay; S E Chang
Journal:  Cell Differ       Date:  1982-05

9.  Characteristics of four new human cell lines derived from squamous cell carcinomas of the head and neck.

Authors:  H T Rupniak; C Rowlatt; E B Lane; J G Steele; L K Trejdosiewicz; B Laskiewicz; S Povey; B T Hill
Journal:  J Natl Cancer Inst       Date:  1985-10       Impact factor: 13.506

10.  Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells.

Authors:  J G Rheinwald; H Green
Journal:  Cell       Date:  1975-11       Impact factor: 41.582

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  1 in total

1.  Relation between antinuclear antibodies and the autoimmune rheumatic diseases and disease type and activity in systemic lupus erythematosus using a variety of cultured cell lines.

Authors:  J Sequi; I Leigh; D A Isenberg
Journal:  Ann Rheum Dis       Date:  1991-03       Impact factor: 19.103

  1 in total

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