Literature DB >> 24478386

Bioethics of organ transplantation.

Arthur Caplan1.   

Abstract

As the ability to transplant organs and tissues has grown, the demand for these procedures has increased as well--to the point at which it far exceeds the available supply creating the core ethical challenge for transplantation--rationing. The gap between supply and demand, although large, is worse than it appears to be. There are two key steps to gaining access to a transplant. First, one must gain access to a transplant center. Then, those waiting need to be selected for a transplant. Many potential recipients do not get admitted to a program. They are deemed too old, not of the right nationality, not appropriate for transplant as a result of severe mental impairment, criminal history, drug abuse, or simply because they do not have access to a competent primary care physician who can refer them to a transplant program. There are also financial obstacles to access to transplant waiting lists in the United States and other nations. In many poor nations, those needing transplants simply die because there is no capacity or a very limited capacity to perform transplants. Although the demand for organs now exceeds the supply, resulting in rationing, the size of waiting lists would quickly expand were there to suddenly be an equally large expansion in the number of organs available for transplantation. Still, even with the reality of unavoidable rationing, saving more lives by increasing organ supply is a moral good. Current public policies for obtaining organs from cadavers are not adequate in that they do not produce the number of organs that public polls of persons in the United States indicate people are willing to donate.

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Year:  2014        PMID: 24478386      PMCID: PMC3935394          DOI: 10.1101/cshperspect.a015685

Source DB:  PubMed          Journal:  Cold Spring Harb Perspect Med        ISSN: 2157-1422            Impact factor:   6.915


  22 in total

1.  Transplantation at any price?

Authors:  Arthur L Caplan
Journal:  Am J Transplant       Date:  2004-12       Impact factor: 8.086

2.  Priority systems in the allocation of organs for transplant: should we reward those who have previously agreed to donate?

Authors:  Jennifer A Chandler
Journal:  Health Law J       Date:  2005

3.  Why we should develop a regulated system of kidney sales: a call for action!

Authors:  Arthur J Matas
Journal:  Clin J Am Soc Nephrol       Date:  2006-10-04       Impact factor: 8.237

4.  Better off living--the ethics of the new UNOS proposal for allocating kidneys for transplantation.

Authors:  Peter P Reese; Arthur L Caplan
Journal:  Clin J Am Soc Nephrol       Date:  2011-09       Impact factor: 8.237

5.  Editorial position on publishing articles on human organ transplantation.

Authors:  Arthur L Caplan; Howard A Rockman; Laurence A Turka
Journal:  J Clin Invest       Date:  2012-01-03       Impact factor: 14.808

6.  Organ procurement: it's not in the cards.

Authors:  A L Caplan
Journal:  Hastings Cent Rep       Date:  1984-10       Impact factor: 2.683

7.  Organ donation and priority points in Israel: an ethical analysis.

Authors:  Muireann Quigley; Linda Wright; Vardit Ravitsky
Journal:  Transplantation       Date:  2012-05-27       Impact factor: 4.939

8.  This is my kidney, I should be able to do with it what I want: towards a legal framework for organ transplants in South Africa.

Authors:  Magda Slabbert
Journal:  Med Law       Date:  2012-12

9.  The impact of presumed consent legislation on cadaveric organ donation: a cross-country study.

Authors:  Alberto Abadie; Sebastien Gay
Journal:  J Health Econ       Date:  2006-02-21       Impact factor: 3.883

10.  Caring for organs or for patients? Ethical concerns about the Uniform Anatomical Gift Act (2006).

Authors:  Michael A DeVita; Arthur L Caplan
Journal:  Ann Intern Med       Date:  2007-12-18       Impact factor: 25.391

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  3 in total

1.  New Kidney and Pancreas Allocation Policy: Moving to a Circle as the First Unit of Allocation.

Authors:  Ajay Israni; Andrew Wey; Bryn Thompson; Jon Miller; Vincent Casingal; Martha Pavlakis; Silke Niederhaus; Rachel Forbes; Amber Wilk; Warren McKinney; Raja Kandaswamy; Peter Stock; Jon Snyder
Journal:  J Am Soc Nephrol       Date:  2021-06-17       Impact factor: 14.978

Review 2.  Organ Transplantation in Iran; Current State and Challenges with a View on Ethical Consideration.

Authors:  Mehrzad Kiani; Mahmoud Abbasi; Mehdi Ahmadi; Bahare Salehi
Journal:  J Clin Med       Date:  2018-03-05       Impact factor: 4.241

Review 3.  Chimeric Humanized Vasculature and Blood: The Intersection of Science and Ethics.

Authors:  Daniel J Garry; Arthur L Caplan; Mary G Garry
Journal:  Stem Cell Reports       Date:  2020-04-14       Impact factor: 7.765

  3 in total

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