Ali Momeni1, Hamid Nasri2. 1. Department of Nephrology, Shahrekord University of Medical Sciences, Shahrekord, Iran. 2. Department of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences,Isfahan, Iran.
Abstract
BACKGROUND: C1q nephropathy (C1qN) is an uncommon glomerulopathy with a significant deposition of C1q in mesangium without clinical evidence of lupus.According to the best of our knowledge, there is not any report on coincidence of diabetes mellitus and C1qN. CASE PRESENTATION: In this report, we presented a 28 years-old-patient with type 1 diabetes and nephrotic range proteinuria, glomerular hematuria and C1q glomerulopathy in renal biopsy. CONCLUSIONS: According to the best of our knowledge, there is no previous report about the association between type 1 DM and C1qN. Prevalence of autoimmune disease is higher in type 1 DM and this may explain the relation between DM and C1qN in our patient.
BACKGROUND:C1qnephropathy (C1qN) is an uncommon glomerulopathy with a significant deposition of C1q in mesangium without clinical evidence of lupus.According to the best of our knowledge, there is not any report on coincidence of diabetes mellitus and C1qN. CASE PRESENTATION: In this report, we presented a 28 years-old-patient with type 1 diabetes and nephrotic range proteinuria, glomerular hematuria and C1qglomerulopathy in renal biopsy. CONCLUSIONS: According to the best of our knowledge, there is no previous report about the association between type 1 DM and C1qN. Prevalence of autoimmune disease is higher in type 1 DM and this may explain the relation between DM and C1qN in our patient.
Authors: Glen S Markowitz; Joshua A Schwimmer; M Barry Stokes; Samih Nasr; Robert L Seigle; Anthony M Valeri; Vivette D D'Agati Journal: Kidney Int Date: 2003-10 Impact factor: 10.612