Literature DB >> 24474092

Attenuation of acne scars using high power fractional ablative unipolar radiofrequency and ultrasound for transepidermal delivery of bioactive compounds through microchannels.

Mario A Trelles1, Pedro A Martínez-Carpio.   

Abstract

BACKGROUND AND
OBJECTIVE: To determine the efficacy and safety of a new method for treating acne scarring over a short-term period of 2 months and a long-term period of 6 months.
MATERIALS AND METHODS: Six faces and 13 shoulders or backs for a total of 19 patients were treated, all of which displayed varying degrees of acne scarring, from moderate to severe. A newly developed high-power unipolar fractional ablative radiofrequency technology was used (iPixel™ RF, Alma Lasers, Caesarea, Israel), with acoustic pressure ultrasound guided dermal injection of the PixelTreat Scars preparation (Alma Lasers), through RF Pixel fractionated microchannels. All patients underwent four treatment sessions at 3-week intervals.
RESULTS: Significant improvement was observed in scarring, both on the face (P < 0.0001), and on the back and shoulders (P < 0.0001). After 2 months, the percentage of fading on total scarring was 57% on the face and 49% on the back and shoulders; after 6 months, the percentage increased to 62% on the face, and 58% on the back and shoulders, respectively. Patients reported to be Somewhat Satisfied (16%), Satisfied (53%), and Very Satisfied (31%). No unexpected side effects to the ablation and no hypersensitive reactions to PixelTreat Scars were observed.
CONCLUSION: The bimodal procedure is safe and effective in reducing acne scarring. This represents a new therapeutic alternative of great interest, to be used either as a monotherapy, or in combination with other treatments.
© 2014 Wiley Periodicals, Inc.

Entities:  

Keywords:  acne scars; cosmeceuticals; fractional ablation; ultrasound; unipolar radiofrequency

Mesh:

Substances:

Year:  2014        PMID: 24474092     DOI: 10.1002/lsm.22224

Source DB:  PubMed          Journal:  Lasers Surg Med        ISSN: 0196-8092            Impact factor:   4.025


  4 in total

1.  Fractional radiofrequency combined with sonophoresis to facilitate skin penetration of 5-aminolevulinic acid.

Authors:  Jong Min Park; Ki-Heon Jeong; Myong Il Bae; Sang-Jun Lee; Nack-In Kim; Min Kyung Shin
Journal:  Lasers Med Sci       Date:  2015-11-12       Impact factor: 3.161

Review 2.  Advances in the treatment of traumatic scars with laser, intense pulsed light, radiofrequency, and ultrasound.

Authors:  Xiujun Fu; Jiying Dong; Shen Wang; Min Yan; Min Yao
Journal:  Burns Trauma       Date:  2019-01-29

Review 3.  A systematic review of treatments for acne scarring. Part 2: Energy-based techniques.

Authors:  Georgios Kravvas; Firas Al-Niaimi
Journal:  Scars Burn Heal       Date:  2018-08-16

Review 4.  Ultrasonography in diagnostic dermatology: a primer for clinicians.

Authors:  Sami Raza; Faisal Ali; Firas Al-Niaimi
Journal:  Arch Dermatol Res       Date:  2022-01-09       Impact factor: 3.017

  4 in total

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