Literature DB >> 24471160

Coupling of tyrosine deprotonation and axial ligand exchange in nitrocytochrome c.

Daiana A Capdevila1, Damián Álvarez-Paggi, María A Castro, Verónica Tórtora, Verónica Demicheli, Darío A Estrín, Rafael Radi, Daniel H Murgida.   

Abstract

Here we report a spectroscopic, electrochemical and computational study of cytochrome c showing that nitration of Tyr74 induces Tyr deprotonation, which is coupled to Met/Lys axial ligand exchange, and results in concomitant gain of peroxidatic activity at physiological pH.

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Year:  2014        PMID： 24471160     DOI： 10.1039/c3cc47207h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

1.  Lysine carbonylation is a previously unrecognized contributor to peroxidase activation of cytochrome c by chloramine-T.

Authors:  Victor Yin; Safee H Mian; Lars Konermann
Journal:  Chem Sci       Date:  2019-01-07       Impact factor: 9.825

Review 2.  Tissue-specific regulation of cytochrome c by post-translational modifications: respiration, the mitochondrial membrane potential, ROS, and apoptosis.

Authors:  Hasini A Kalpage; Viktoriia Bazylianska; Maurice A Recanati; Alemu Fite; Jenney Liu; Junmei Wan; Nikhil Mantena; Moh H Malek; Izabela Podgorski; Elizabeth I Heath; Asmita Vaishnav; Brian F Edwards; Lawrence I Grossman; Thomas H Sanderson; Icksoo Lee; Maik Hüttemann
Journal:  FASEB J       Date:  2018-09-17       Impact factor: 5.834
  2 in total

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