Literature DB >> 24470093

Manganese in health and disease.

Daiana Silva Avila1, Robson Luiz Puntel, Michael Aschner.   

Abstract

Manganese is an important metal for human health, being absolutely necessary for development, metabolism, and the antioxidant system. Nevertheless, excessive exposure or intake may lead to a condition known as manganism, a neurodegenerative disorder that causes dopaminergic neuronal death and parkinsonian-like symptoms. Hence, Mn has a paradoxal effect in animals, a Janus-faced metal. Extensive work has been carried out to understand Mn-induced neurotoxicity and to find an effective treatment. This review focuses on the requirement for Mn in human health as well as the diseases associated with excessive exposure to this metal.

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Year:  2013        PMID: 24470093      PMCID: PMC6589086          DOI: 10.1007/978-94-007-7500-8_7

Source DB:  PubMed          Journal:  Met Ions Life Sci        ISSN: 1559-0836


  48 in total

1.  Peumus boldus (Boldo) Aqueous Extract Present Better Protective Effect than Boldine Against Manganese-Induced Toxicity in D. melanogaster.

Authors:  Matheus Chimelo Bianchini; Claudia Ortiz Alves Gularte; Dandara Fidélis Escoto; Geovana Pereira; Mateus Cristofari Gayer; Rafael Roehrs; Félix Alexandre Antunes Soares; Robson L Puntel
Journal:  Neurochem Res       Date:  2016-06-27       Impact factor: 3.996

2.  The association between deficient manganese levels and breast cancer: a meta-analysis.

Authors:  Fei Shen; Wen-Song Cai; Jiang-Lin Li; Zhe Feng; Jie Cao; Bo Xu
Journal:  Int J Clin Exp Med       Date:  2015-03-15

Review 3.  Role of transcription factor yin yang 1 in manganese-induced reduction of astrocytic glutamate transporters: Putative mechanism for manganese-induced neurotoxicity.

Authors:  Pratap Karki; Keisha Smith; James Johnson; Michael Aschner; Eunsook Lee
Journal:  Neurochem Int       Date:  2014-08-13       Impact factor: 3.921

Review 4.  Influence of iron metabolism on manganese transport and toxicity.

Authors:  Qi Ye; Jo Eun Park; Kuljeet Gugnani; Swati Betharia; Alejandro Pino-Figueroa; Jonghan Kim
Journal:  Metallomics       Date:  2017-08-16       Impact factor: 4.526

Review 5.  Redox dynamics of manganese as a mitochondrial life-death switch.

Authors:  Matthew Ryan Smith; Jolyn Fernandes; Young-Mi Go; Dean P Jones
Journal:  Biochem Biophys Res Commun       Date:  2017-02-03       Impact factor: 3.575

6.  The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis.

Authors:  Ivo Florin Scheiber; Yuze Wu; Shannon Elizabeth Morgan; Ningning Zhao
Journal:  J Biol Chem       Date:  2019-04-26       Impact factor: 5.157

7.  Effect of olfactory manganese exposure on anxiety-related behavior in a mouse model of iron overload hemochromatosis.

Authors:  Qi Ye; Jonghan Kim
Journal:  Environ Toxicol Pharmacol       Date:  2015-06-23       Impact factor: 4.860

8.  Diphenyl Diselenide Protects Against Mortality, Locomotor Deficits and Oxidative Stress in Drosophila melanogaster Model of Manganese-Induced Neurotoxicity.

Authors:  Isaac A Adedara; Amos O Abolaji; Joao B T Rocha; Ebenezer O Farombi
Journal:  Neurochem Res       Date:  2016-02-15       Impact factor: 3.996

9.  Trace elements as predictors of preeclampsia in type 1 diabetic pregnancy.

Authors:  Arpita Basu; Jeremy Y Yu; Alicia J Jenkins; Alison J Nankervis; Kristian F Hanssen; Tore Henriksen; Bjørg Lorentzen; Satish K Garg; M Kathryn Menard; Samar M Hammad; James A Scardo; Christopher E Aston; Timothy J Lyons
Journal:  Nutr Res       Date:  2015-04-11       Impact factor: 3.315

10.  Mitochondria represent another locale for the divalent metal transporter 1 (DMT1).

Authors:  Natascha A Wolff; Laura M Garrick; Lin Zhao; Michael D Garrick; Frank Thévenod
Journal:  Channels (Austin)       Date:  2014       Impact factor: 2.581

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