Literature DB >> 2446910

Cardiac calcium currents at the level of single channels.

R W Tsien1, B Nilius.   

Abstract

Properties of cardiac Ca channels have come into sharper focus with the advent of single cell preparations and suction pipette recording methods. We briefly summarize our present picture of the gating and permeation properties of the conventional, dihydropyridine-sensitive type of Ca channel (L-type). Distinctive features of a second type of voltage-gated Ca channel (T-type) are discussed.

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Year:  1987        PMID: 2446910     DOI: 10.1007/bf01945517

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  32 in total

1.  Existence and role of a slow inward current during the frog atrial action potential.

Authors:  O Rougier; G Vassort; D Garnier; Y M Gargouil; E Coraboeuf
Journal:  Pflugers Arch       Date:  1969       Impact factor: 3.657

2.  Beta-adrenergic increase in the calcium conductance of cardiac myocytes studied with the patch clamp.

Authors:  G Brum; W Osterrieder; W Trautwein
Journal:  Pflugers Arch       Date:  1984-06       Impact factor: 3.657

3.  Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches.

Authors:  O P Hamill; A Marty; E Neher; B Sakmann; F J Sigworth
Journal:  Pflugers Arch       Date:  1981-08       Impact factor: 3.657

4.  Beta-adrenergic modulation of calcium channels in frog ventricular heart cells.

Authors:  B P Bean; M C Nowycky; R W Tsien
Journal:  Nature       Date:  1984 Jan 26-Feb 1       Impact factor: 49.962

5.  Mechanism of ion permeation through calcium channels.

Authors:  P Hess; R W Tsien
Journal:  Nature       Date:  1984 May 31-Jun 6       Impact factor: 49.962

6.  Membrane calcium current in ventricular myocardial fibres.

Authors:  G W Beeler; H Reuter
Journal:  J Physiol       Date:  1970-03       Impact factor: 5.182

7.  Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.

Authors:  B P Bean
Journal:  Proc Natl Acad Sci U S A       Date:  1984-10       Impact factor: 11.205

8.  Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells.

Authors:  K S Lee; R W Tsien
Journal:  Nature       Date:  1983-04-28       Impact factor: 49.962

9.  Dihydropyridine derivatives prolong the open state of Ca channels in cultured cardiac cells.

Authors:  S Kokubun; H Reuter
Journal:  Proc Natl Acad Sci U S A       Date:  1984-08       Impact factor: 11.205

10.  Calcium channel selectivity for divalent and monovalent cations. Voltage and concentration dependence of single channel current in ventricular heart cells.

Authors:  P Hess; J B Lansman; R W Tsien
Journal:  J Gen Physiol       Date:  1986-09       Impact factor: 4.086

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  3 in total

1.  The use of calcium blockers to study biochemical behaviour of Saccharomyces cerevisiae cells.

Authors:  R de Souza Pereira
Journal:  Mol Cell Biochem       Date:  2001-12       Impact factor: 3.396

2.  Dihydropyridine block of voltage-dependent K+ currents in rat dorsal root ganglion neurons.

Authors:  X-L Zhang; M S Gold
Journal:  Neuroscience       Date:  2009-03-13       Impact factor: 3.590

3.  Voltage-gated calcium channel antagonists and traumatic brain injury.

Authors:  Gene Gurkoff; Kiarash Shahlaie; Bruce Lyeth; Robert Berman
Journal:  Pharmaceuticals (Basel)       Date:  2013-06-26
  3 in total

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