Literature DB >> 2446882

The ability of des-Arg9-bradykinin to relax rabbit isolated mesenteric arteries is acquired during in vitro incubation.

D Deblois1, F Marceau.   

Abstract

Strips of rabbit mesenteric arteries precontracted with phenylephrine relaxed when exposed to des-Arg9-bradykinin (BK), a typical B1 receptor agonist. We showed that the ability of des-Arg9-BK to relax this preparation was acquired during in vitro incubation and was abolished by cycloheximide treatment. In this preparation intimal damage reduced but did not abolish the relaxant effect of des-Arg9-BK, and indomethacin uncovered a contractile effect of des-Arg9-BK also acquired during the in vitro incubation.

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Year:  1987        PMID： 2446882     DOI： 10.1016/0014-2999(87)90664-9

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  15 in total

1.  Endotoxin sensitization to kinin B(1) receptor agonist in a non-human primate model: haemodynamic and pro-inflammatory effects.

Authors:  D deBlois; R A Horlick
Journal:  Br J Pharmacol       Date:  2001-01       Impact factor: 8.739

2.  Selective labelling of bradykinin receptor subtypes in WI38 human lung fibroblasts.

Authors:  S B Phagoo; M Yaqoob; M C Brown; G M Burgess
Journal:  Br J Pharmacol       Date:  1996-11       Impact factor: 8.739

3.  Endothelial kinin B(1)-receptors are induced by myocardial ischaemia-reperfusion in the rabbit.

Authors:  C Mazenot; L Loufrani; D Henrion; C Ribuot; W Muller-Esterl; D Godin-Ribuot
Journal:  J Physiol       Date:  2001-01-01       Impact factor: 5.182

4.  Induction of kinin B1 receptor-dependent vasoconstriction following balloon catheter injury to the rabbit carotid artery.

Authors:  D Pruneau; J M Luccarini; C Robert; P Bélichard
Journal:  Br J Pharmacol       Date:  1994-04       Impact factor: 8.739

5.  Vascular mode of action of kinin B1 receptors and development of a cellular model for the investigation of these receptors.

Authors:  L Levesque; G Drapeau; J H Grose; F Rioux; F Marceau
Journal:  Br J Pharmacol       Date:  1993-08       Impact factor: 8.739

6.  Human interleukin-1 induces a rapid relaxation of the rabbit isolated mesenteric artery.

Authors:  F Marceau; E Petitclerc; D DeBlois; P Pradelles; P E Poubelle
Journal:  Br J Pharmacol       Date:  1991-06       Impact factor: 8.739

7.  Endothelium-dependent relaxations mediated by inducible B1 and constitutive B2 kinin receptors in the bovine isolated coronary artery.

Authors:  G R Drummond; T M Cocks
Journal:  Br J Pharmacol       Date:  1995-11       Impact factor: 8.739

8.  Protective effects of bradykinin on the ischaemic heart: implication of the B1 receptor.

Authors:  R Chahine; A Adam; N Yamaguchi; R Gaspo; D Regoli; R Nadeau
Journal:  Br J Pharmacol       Date:  1993-02       Impact factor: 8.739

9.  Pulse exposure to protein synthesis inhibitors enhances vascular responses to des-Arg9-bradykinin: possible role of interleukin-1.

Authors:  D deBlois; J Bouthillier; F Marceau
Journal:  Br J Pharmacol       Date:  1991-05       Impact factor: 8.739

10.  Up-regulation of [3H]-des-Arg10-kallidin binding to the bradykinin B1 receptor by interleukin-1 beta in isolated smooth muscle cells: correlation with B1 agonist-induced PGI2 production.

Authors:  J P Galizzi; M C Bodinier; B Chapelain; S M Ly; L Coussy; S Giraud; G Neliat; T Jean
Journal:  Br J Pharmacol       Date:  1994-10       Impact factor: 8.739
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