Ivy H Gardner1, Joshua D Safer. 1. Section of Endocrinology, Boston University School of Medicine, Boston, Massachusetts, USA.
Abstract
PURPOSE OF REVIEW: In order to improve transgender individuals' access to healthcare, primary care physicians and specialists alike should be knowledgeable about transgender medicine. This review is intended to provide concise transgender hormone treatment guidelines. RECENT FINDINGS: Transgender individuals report that the lack of knowledgeable providers represents the greatest barrier to transgender medical care. Hormone treatments are generally well tolerated and greatly benefit transgender patients. After physicians recognize that gender identity is stable, hormone treatments for transgender patients are often straightforward. A practical target for hormone therapy for transgender men (female to male) is to increase testosterone levels to the normal male physiological range (300-1000 ng/dl) by administering testosterone. A practical target for hormone therapy for transgender women (male to female) is to decrease testosterone levels to the normal female range (30-100 ng/dl) without supra-physiological levels of estradiol (<200 pg/ml) by administering an antiandrogen and estrogen. Patients should be monitored every 3 months for the first year and then every 6-12 months for hormonal effects. SUMMARY: Although more studies are required, recently published transgender medical treatment guidelines provide a good start toward making care of transgender patients more generalized and accessible to healthcare providers.
PURPOSE OF REVIEW: In order to improve transgender individuals' access to healthcare, primary care physicians and specialists alike should be knowledgeable about transgender medicine. This review is intended to provide concise transgender hormone treatment guidelines. RECENT FINDINGS: Transgender individuals report that the lack of knowledgeable providers represents the greatest barrier to transgender medical care. Hormone treatments are generally well tolerated and greatly benefit transgender patients. After physicians recognize that gender identity is stable, hormone treatments for transgender patients are often straightforward. A practical target for hormone therapy for transgender men (female to male) is to increase testosterone levels to the normal male physiological range (300-1000 ng/dl) by administering testosterone. A practical target for hormone therapy for transgender women (male to female) is to decrease testosterone levels to the normal female range (30-100 ng/dl) without supra-physiological levels of estradiol (<200 pg/ml) by administering an antiandrogen and estrogen. Patients should be monitored every 3 months for the first year and then every 6-12 months for hormonal effects. SUMMARY: Although more studies are required, recently published transgender medical treatment guidelines provide a good start toward making care of transgender patients more generalized and accessible to healthcare providers.
Authors: Joseph Gerth; Tracy Becerra-Culqui; Andrew Bradlyn; Darios Getahun; Enid M Hunkeler; Timothy L Lash; Andrea Millman; Rebecca Nash; Virginia P Quinn; Brandi Robinson; Douglas Roblin; Michael J Silverberg; Vin Tangpricha; Suma Vupputuri; Michael Goodman Journal: Rev Endocr Metab Disord Date: 2018-09 Impact factor: 6.514
Authors: Douglas Roblin; Joshua Barzilay; Dennis Tolsma; Brandi Robinson; Laura Schild; Lee Cromwell; Hayley Braun; Rebecca Nash; Joseph Gerth; Enid Hunkeler; Virginia P Quinn; Vin Tangpricha; Michael Goodman Journal: Ann Epidemiol Date: 2016-02-04 Impact factor: 3.797
Authors: Max Lichtenstein; Laura Stein; Erin Connolly; Zil G Goldstein; Tyler Martinson; Linda Tiersten; Sangyoon J Shin; John Henry Pang; Joshua D Safer Journal: Transgend Health Date: 2020-09-02