| Literature DB >> 24468317 |
Giulia Perrone, Perrone Giulia1, Paolo Corradini2.
Abstract
Peripheral T-cell lymphomas (PTCLs) are a rare and heterogeneous group of T-cell malignancies characterized by a very poor outcome. The optimal treatment for PTCLs remains controversial. The role of stem cell transplantation in PTCLs has been investigated; however, no randomized control studies specifically dedicated to PTCLs are currently available. Several retrospective and prospective studies have suggested that high-dose chemotherapy (HDT) followed by autologous stem cell transplantation (ASCT) may improve the survival in patients with chemosensitive T-cell lymphoma, either upfront or as salvage treatment. This review provides a summary of the current literature with the intent to explore the role of ASCT in various clinical scenarios.Entities:
Mesh:
Year: 2013 PMID: 24468317 DOI: 10.1053/j.seminhematol.2013.11.002
Source DB: PubMed Journal: Semin Hematol ISSN: 0037-1963 Impact factor: 3.851