| Literature DB >> 24467935 |
Eduardo Ibargüen-Mondragón1, Saulo Mosquera2, Miller Cerón2, Edith Mariela Burbano-Rosero3, Sandra P Hidalgo-Bonilla4, Lourdes Esteva5, Jhoana P Romero-Leitón6.
Abstract
We formulate a mathematical model that describes the population dynamics of bacteria exposed to multiple antibiotics simultaneously, assuming that acquisition of resistance is through mutations due to antibiotic exposure. Qualitative analysis reveals the existence of a free-bacteria equilibrium, resistant-bacteria equilibrium and an endemic equilibrium where both bacteria coexist.Keywords: Antibiotics; Bacterial resistance; Equilibrium solutions; Ordinary differential equations
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Year: 2014 PMID： 24467935 DOI： 10.1016/j.biosystems.2014.01.005
Source DB: PubMed Journal: Biosystems ISSN： 0303-2647 Impact factor: 1.973