Literature DB >> 2446651

Treatment of chronic venous ulcers with sheets of cultured allogenic keratinocytes.

I M Leigh1, P E Purkis, H A Navsaria, T J Phillips.   

Abstract

Cultured keratinocytes were used as allografts to treat 51 patients with chronic venous ulceration or rheumatoid ulcers unresponsive to all previous conventional treatments including split skin grafts. Although early epithelialization could be seen in the centre of some ulcers, a major effect appeared to be healing from the previously indolent edge. This treatment appears to provide some clinical benefit in healing of chronic ulceration.

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Year:  1987        PMID： 2446651     DOI： 10.1111/j.1365-2133.1987.tb07491.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN： 0007-0963            Impact factor:   9.302


  20 in total

1.  Relation between antinuclear antibodies and the autoimmune rheumatic diseases and disease type and activity in systemic lupus erythematosus using a variety of cultured cell lines.

Authors:  J Sequi; I Leigh; D A Isenberg
Journal:  Ann Rheum Dis       Date:  1991-03       Impact factor: 19.103

2.  Advantages of using a bank of allogenic keratinocytes for the rapid coverage of extensive and deep second-degree burns.

Authors:  F Braye; P Pascal; M Bertin-Maghit; J J Colpart; E Tissot; O Damour
Journal:  Med Biol Eng Comput       Date:  2000-03       Impact factor: 2.602

3.  Common antigen expression between human periderm and other tissues identified by GB1-monoclonal antibody.

Authors:  O M Schofield; J N McDonald; D Fredj-Reygrobellet; B L Hsi; C J Yeh; J P Ortonne; R A Eady
Journal:  Arch Dermatol Res       Date:  1990       Impact factor: 3.017

Review 4.  Cultured keratinocytes and keratinocyte grafts.

Authors:  K Hancock; I M Leigh
Journal:  BMJ       Date:  1989-11-11

5.  Survival of cultured allogeneic keratinocytes transplanted to deep dermal bed assessed with probe specific for Y chromosome.

Authors:  A Brain; P Purkis; P Coates; M Hackett; H Navsaria; I Leigh
Journal:  BMJ       Date:  1989-04-08

6.  Clinical interest of cutaneous models reproduced in vitro for severe burn treatment: histopathological and ultrastructural study.

Authors:  Y Neveux; J M Rives; C Le Breton; E Gentilhomme; P Saint-Blancar; H Carsin
Journal:  Cell Biol Toxicol       Date:  1995-08       Impact factor: 6.691

7.  Survival of cultured allografts in patients with burns assessed with probe specific for Y chromosome.

Authors:  A M Burt; C D Pallett; J P Sloane; M J O'Hare; K F Schafler; P Yardeni; A Eldad; J A Clarke; B A Gusterson
Journal:  BMJ       Date:  1989-04-08

Review 8.  Regenerative medicine as applied to general surgery.

Authors:  Giuseppe Orlando; Kathryn J Wood; Paolo De Coppi; Pedro M Baptista; Kyle W Binder; Khalil N Bitar; Christopher Breuer; Luke Burnett; George Christ; Alan Farney; Marina Figliuzzi; James H Holmes; Kenneth Koch; Paolo Macchiarini; Sayed-Hadi Mirmalek Sani; Emmanuel Opara; Andrea Remuzzi; Jeffrey Rogers; Justin M Saul; Dror Seliktar; Keren Shapira-Schweitzer; Tom Smith; Daniel Solomon; Mark Van Dyke; James J Yoo; Yuanyuan Zhang; Anthony Atala; Robert J Stratta; Shay Soker
Journal:  Ann Surg       Date:  2012-05       Impact factor: 12.969

9.  Transplantation of chronic wounds with epidermal sheets derived from autologous hair follicles--the Leipzig experience.

Authors:  Regina Renner; Wolfgang Harth; Jan C Simon
Journal:  Int Wound J       Date:  2009-06       Impact factor: 3.315

10.  Mathematical model for wound healing following autologous keratinocyte transplantation.

Authors:  Regina Renner; Isabell Teuwen; Carl Gebhardt; Jan C Simon
Journal:  Int Wound J       Date:  2008-06       Impact factor: 3.315
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