Literature DB >> 24462321

6-Mercaptopurine/Azathioprine remains an important contributor in managing Crohn's disease.

Burton I Korelitz1, Daniel H Present2.   

Abstract

Two large studies concluded that AZA started early after diagnosis of Crohn's disease have no late maintenance value. This is contrary to previous studies on 6MP for Crohn's disease and could lead to negating the value of two of the few drugs that have been proven successful. We here outline the many reasons why 6MP remains a valuable drug in the treatment of Crohn's disease.
Copyright © 2014 European Crohn's and Colitis Organisation. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  6-Mercaptopurine; Azathioprine; Crohn's disease

Mesh:

Substances:

Year:  2014        PMID: 24462321     DOI: 10.1016/j.crohns.2013.12.024

Source DB:  PubMed          Journal:  J Crohns Colitis        ISSN: 1873-9946            Impact factor:   9.071


  2 in total

1.  Enduring Value of Thiopurines for Inflammatory Bowel Disease Therapy.

Authors:  Burton I Korelitz
Journal:  Dig Dis Sci       Date:  2017-02       Impact factor: 3.199

Review 2.  Thiopurines and inflammatory bowel disease: Current evidence and a historical perspective.

Authors:  Jordan E Axelrad; Abhik Roy; Garrett Lawlor; Burton Korelitz; Simon Lichtiger
Journal:  World J Gastroenterol       Date:  2016-12-14       Impact factor: 5.742

  2 in total

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