Literature DB >> 24460784

Effect of early long-pulse pulsed dye laser treatment in infantile hemangiomas.

Soon Hyo Kwon1, Jae Woo Choi, Sang Young Byun, Bo Ri Kim, Kyoung Chan Park, Sang Woong Youn, Chang Hun Huh, Jung Im Na.   

Abstract

BACKGROUND: Despite several recent reports on the efficacy of long-pulse pulsed dye laser (LP-PDL) in treating infantile hemangiomas, controversy remains.
OBJECTIVES: To determine the beneficial effects of early therapeutic intervention with LP-PDL in superficial and mixed hemangiomas. METHODS AND MATERIALS: Clinical data from 40 children with 47 hemangiomas in preproliferative or proliferative phase treated with LP-PDL in a Korean tertiary hospital over 5 years were analyzed retrospectively. Treatments were repeated at 1- to 4-week intervals until growth stopped.
RESULTS: Of the 47 hemangiomas, 32 were superficial, and 15 were mixed at presentation. Age was 9.6 ± 5.9 weeks at initiation of treatment and 18.0 ± 8.6 weeks at completion, and a positive linear correlation existed between the two. There were a mean of 4.6 ± 2.6 treatments per hemangioma, which was lower in superficial than in mixed hemangiomas. Improvement in color was documented in 84.4% of superficial and 86.7% of mixed hemangiomas, and 75.0% of superficial and 66.7% of mixed shrank. Hyperpigmentation occurred in two superficial hemangiomas.
CONCLUSION: Early intervention in hemangiomas using LP-PDL successfully prevents further growth and accelerates a transition to plateau or involution phase with minimal adverse events, achieving good cosmetic outcomes.
© 2014 by the American Society for Dermatologic Surgery, Inc. Published by Wiley Periodicals, Inc.

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Year:  2014        PMID: 24460784     DOI: 10.1111/dsu.12451

Source DB:  PubMed          Journal:  Dermatol Surg        ISSN: 1076-0512            Impact factor:   3.398


  6 in total

1.  Effective treatment for infantile hemangioma with long-pulsed dye laser with oral propranolol medication: a preliminary report.

Authors:  Shigeyuki Furuta; Hideaki Sato; Shiho Tsuji; Fumiko Murakami; Hiroaki Kitagawa
Journal:  Pediatr Surg Int       Date:  2016-07-26       Impact factor: 1.827

2.  Morphological, genetic and clinical correlations in infantile hemangiomas and their mimics.

Authors:  Alina Costina Luca; Ingrith Crenguţa Miron; Laura Mihaela Trandafir; Elena Cojocaru; Ioana Alexandra Pădureţ; Mioara Florentina Trandafirescu; Alin Constantin Iordache; Elena Ţarcă
Journal:  Rom J Morphol Embryol       Date:  2020 Jul-Sep       Impact factor: 1.033

Review 3.  The role of lasers and intense pulsed light technology in dermatology.

Authors:  Zain Husain; Tina S Alster
Journal:  Clin Cosmet Investig Dermatol       Date:  2016-02-04

4.  Efficacy of propranolol and pingyangmycin, respectively, combined with pulsed dye laser on children with hemangioma.

Authors:  Zhiyong Huang; Ning Zhang; Hanxin Cai; Kunhui Luo
Journal:  Exp Ther Med       Date:  2019-12-11       Impact factor: 2.447

5.  Oral propranolol combined with topical timolol for compound infantile hemangiomas: a retrospective study.

Authors:  Jing Ge; Jiawei Zheng; Ling Zhang; Weien Yuan; Haiguang Zhao
Journal:  Sci Rep       Date:  2016-01-28       Impact factor: 4.379

6.  Clinical Characteristics and Treatment Options of Infantile Vascular Anomalies.

Authors:  Bin Yang; Li Li; Li-Xin Zhang; Yu-Juan Sun; Lin Ma
Journal:  Medicine (Baltimore)       Date:  2015-10       Impact factor: 1.817

  6 in total

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