Literature DB >> 24460453

Is methotrexate administration needed for the treatment of caesarean section scar pregnancy in addition to suction curettage?

Osman Sevket1, Seda Keskin, Seda Ates, Taner Molla, Ramazan Dansuk, Hasan Fehmi Yazicioglu, Oguz Yucel.   

Abstract

OBJECTIVE: This study evaluated the clinical outcomes and safety of treating caesarean scar pregnancy (CSP) by means of suction curettage followed when required by Foley tamponade, with or without methotrexate (MTX) therapy preceding the curettage.
METHODS: Twenty-five patients with CSP were identified between August 2008 and April 2012. The first team of doctors treated Group A patients (n = 11) with systemic MTX followed by dilatation and suction curettage whereas the second team of doctors carried out only a suction curettage on women of Group B (n = 14). If uncontrolled vaginal bleeding occurred in either group during or after the operation, a Foley catheter, guided by real time transabdominal ultrasound, was placed in the uterine cavity against the site where the CSP had been implanted.
RESULTS: Clinical outcomes in the two groups - including mean estimated blood loss, major complication rate, and hospital length of stay - were comparable. Surgeons used Foley catheter balloons for tamponade in six of the 11 patients in Group A and in seven of the 14 patients in Group B. Treatment was successful in ten of 11 cases in group A and 13 of 14 cases in group B. Group B's mean duration of treatment (2.36 ± 0.49 days) was significantly shorter than that of Group A (14.45 ± 4.96 days; p < 0.001).
CONCLUSION: Suction curettage, followed when needed by Foley catheter tamponade, is an effective treatment for CSP.

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Year:  2014        PMID: 24460453     DOI: 10.3109/13625187.2013.873400

Source DB:  PubMed          Journal:  Eur J Contracept Reprod Health Care        ISSN: 1362-5187            Impact factor:   1.848


  2 in total

1.  The value of transvaginal ultrasound in clinical surgical treatment of cesarean scar pregnancy.

Authors:  Zhen Zeng; Shu-Ping Ding; Xue Zeng; Sui Cao; Ling-Yu Wei; Yan-Yan Liu; Fu-Yan Yang; Jing-Ji Gong; Han-Ping Chen; Xiao-Yan Xu
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2017-08-08

2.  Evaluation of treatment of previous cesarean scar pregnancy with methotrexate: a systematic review and meta-analysis.

Authors:  Nader Salari; Mohsen Kazeminia; Shamarina Shohaimi; Anis Al-Dawlah Nankali; Masoud Mohammadi
Journal:  Reprod Biol Endocrinol       Date:  2020-11-09       Impact factor: 5.211

  2 in total

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