Literature DB >> 24458274

Core fucosylation and IgG function in NAIT.

Richard H Aster1.   

Abstract

In this issue of Blood, Kapur et al show that maternal human platelet-specific antigen 1a (HPA 1a)-specific antibodies causing neonatal alloimmune thrombocytopenia (NAIT) possess oligosaccharides that are deficient in "core fucose" residues and appear to be more effective than fucosylated antibodies in promoting phagocytosis of antibody-coated platelets.

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Year:  2014        PMID： 24458274      PMCID： PMC3901063          DOI： 10.1182/blood-2013-12-539965

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  10 in total

1.  Divergent immunoglobulin g subclass activity through selective Fc receptor binding.

Authors:  Falk Nimmerjahn; Jeffrey V Ravetch
Journal:  Science       Date:  2005-12-02       Impact factor: 47.728

2.  Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity.

Authors:  Falk Nimmerjahn; Robert M Anthony; Jeffrey V Ravetch
Journal:  Proc Natl Acad Sci U S A       Date:  2007-05-07       Impact factor: 11.205

Review 3.  Recombinant antibody therapeutics: the impact of glycosylation on mechanisms of action.

Authors:  Royston Jefferis
Journal:  Trends Pharmacol Sci       Date:  2009-06-22       Impact factor: 14.819

4.  Unique carbohydrate-carbohydrate interactions are required for high affinity binding between FcgammaRIII and antibodies lacking core fucose.

Authors:  Claudia Ferrara; Sandra Grau; Christiane Jäger; Peter Sondermann; Peter Brünker; Inja Waldhauer; Michael Hennig; Armin Ruf; Arne Christian Rufer; Martine Stihle; Pablo Umaña; Jörg Benz
Journal:  Proc Natl Acad Sci U S A       Date:  2011-07-18       Impact factor: 11.205

5.  Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity.

Authors:  Robert L Shields; Jadine Lai; Rodney Keck; Lori Y O'Connell; Kyu Hong; Y Gloria Meng; Stefanie H A Weikert; Leonard G Presta
Journal:  J Biol Chem       Date:  2002-05-01       Impact factor: 5.157

6.  The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity.

Authors:  Toyohide Shinkawa; Kazuyasu Nakamura; Naoko Yamane; Emi Shoji-Hosaka; Yutaka Kanda; Mikiko Sakurada; Kazuhisa Uchida; Hideharu Anazawa; Mitsuo Satoh; Motoo Yamasaki; Nobuo Hanai; Kenya Shitara
Journal:  J Biol Chem       Date:  2002-11-08       Impact factor: 5.157

Review 7.  Neonatal alloimmune thrombocytopenia: pathogenesis, diagnosis and management.

Authors:  Julie A Peterson; Janice G McFarland; Brian R Curtis; Richard H Aster
Journal:  Br J Haematol       Date:  2013-02-06       Impact factor: 6.998

8.  General mechanism for modulating immunoglobulin effector function.

Authors:  Peter Sondermann; Andrew Pincetic; Jad Maamary; Katja Lammens; Jeffrey V Ravetch
Journal:  Proc Natl Acad Sci U S A       Date:  2013-05-22       Impact factor: 11.205

Review 9.  Glycosylation as a strategy to improve antibody-based therapeutics.

Authors:  Roy Jefferis
Journal:  Nat Rev Drug Discov       Date:  2009-03       Impact factor: 84.694

10.  A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy.

Authors:  Rick Kapur; Iwan Kustiawan; Anne Vestrheim; Carolien A M Koeleman; Remco Visser; Helga K Einarsdottir; Leendert Porcelijn; Dave Jackson; Belinda Kumpel; André M Deelder; Dennis Blank; Björn Skogen; Mette Kjaer Killie; Terje E Michaelsen; Masja de Haas; Theo Rispens; C Ellen van der Schoot; Manfred Wuhrer; Gestur Vidarsson
Journal:  Blood       Date:  2013-11-15       Impact factor: 22.113
  10 in total
  1 in total

1.  Machine Learning Classifies Core and Outer Fucosylation of N-Glycoproteins Using Mass Spectrometry.

Authors:  Heeyoun Hwang; Hoi Keun Jeong; Hyun Kyoung Lee; Gun Wook Park; Ju Yeon Lee; Soo Youn Lee; Young-Mook Kang; Hyun Joo An; Jeong Gu Kang; Jeong-Heon Ko; Jin Young Kim; Jong Shin Yoo
Journal:  Sci Rep       Date:  2020-01-15       Impact factor: 4.379
  1 in total

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