Hydroxyamination of aryl C-H bonds with N-hydroxycarbamate by synergistic Rh/Cu catalysis at room temperature.

A novel hydroamination of aryl C-H bonds has been accomplished using N-Boc-hydroxyamine via synergistic combination of rhodium and copper catalysis. The merger of two robust catalytic systems has allowed for the development of a mild and sustainable protocol for the direct formation of benzo[c]isoxazol-3(1H)-ones.