G Li1, P Xu1, X Pan1, H Qin1, Y Chen2. 1. Department of Radiology, East Hospital, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China. 2. Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China. Electronic address: c.y.m@126.com.
Abstract
AIM: To investigate and characterize the effect of age on apparent diffusion coefficient (ADC) values in normal spleen. MATERIALS AND METHODS: A population of 127 patients (age range 10-79 years, mean age 44.4 years) without magnetic resonance imaging findings in abdominal scans, was selected over a 5-year period. The ADC values of the spleen were analysed in all ages, and dependency of ADC values on age was characterized using Spearman's correlation coefficient test. RESULTS: A reduction of ADC values with ageing was found in the spleen (r = -0.702, p < 0.001). CONCLUSIONS: The ADC values of the spleen decline with age. This should be taken into consideration when disease is diagnosed.
AIM: To investigate and characterize the effect of age on apparent diffusion coefficient (ADC) values in normal spleen. MATERIALS AND METHODS: A population of 127 patients (age range 10-79 years, mean age 44.4 years) without magnetic resonance imaging findings in abdominal scans, was selected over a 5-year period. The ADC values of the spleen were analysed in all ages, and dependency of ADC values on age was characterized using Spearman's correlation coefficient test. RESULTS: A reduction of ADC values with ageing was found in the spleen (r = -0.702, p < 0.001). CONCLUSIONS: The ADC values of the spleen decline with age. This should be taken into consideration when disease is diagnosed.