| Literature DB >> 2445601 |
O Närvänen1, A Närvänen, V M Wasenius, P Partanen, I Virtanen.
Abstract
A monoclonal antibody (Mab) against a synthetic peptide, SEDYGKDL, corresponding to one conserved sequence in the chicken alpha-fodrin repeats reacts in immunoblotting with avian alpha-spectrin and alpha-fodrin, both mammalian spectrins and with mammalian alpha-fodrin. This Mab also reacts with alpha-actinin in both chicken and human cells. Our results confirm the previously detected structural homology between spectrins and alpha-actinin and implicate their common evolutionary origin.Entities:
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Year: 1987 PMID: 2445601 DOI: 10.1016/0014-5793(87)80440-4
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124