Literature DB >> 2445279

[Ampicillin pharmacokinetics in prostatic adenoma patients].

V P Iakovlev, L Z Skala, R A Slobodskoĭ, A G Nekhorosheva, L A Lur'e.   

Abstract

Studies on ampicillin pharmacokinetics in patients with prostate adenoma showed that adenoma did not influence the antibiotic kinetics. The ampicillin maximum concentration in tissues and organs of the urinary corresponded to the peak concentrations in blood. Therefore, development of dosage regimens providing the drug efficient concentrations in tissues and organs of the urinary tract should be based on ampicillin kinetics in the blood.

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Year:  1987        PMID: 2445279

Source DB:  PubMed          Journal:  Antibiot Med Biotekhnol        ISSN: 0233-7525


  1 in total

1.  Penetration of a single infusion of ampicillin and sulbactam into prostatic tissue during transurethral prostatectomy.

Authors:  T Klotz; M Braun; A Bin Saleh; M Orlovski; U Engelmann
Journal:  Int Urol Nephrol       Date:  1999       Impact factor: 2.370

  1 in total

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