Literature DB >> 24452461

Cinchona alkaloids from Cinchona succirubra and Cinchona ledgeriana.

Gui-Guang Cheng1, Xiang-Hai Cai1, Bao-Hong Zhang2, Yan Li1, Ji Gu1, Mei-Fen Bao1, Ya-Ping Liu1, Xiao-Dong Luo1.   

Abstract

Seven new cinchona alkaloids, cinchonanines A-G (1-7), and 29 known alkaloids were isolated from the barks of Cinchona surrirubra and C. ledgeriana collected from Yunnan Province in China. The new structures were elucidated by extensive spectroscopic analysis. All compounds were evaluated for their cytotoxicity against five human cancer cell lines. Compounds 2, 13, 14, and 15 showed moderate cytotoxicity. Georg Thieme Verlag KG Stuttgart · New York.

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Year:  2014        PMID: 24452461     DOI: 10.1055/s-0033-1360279

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  1 in total

1.  Cytotoxic Indole Alkaloid 3α-Acetonyltabersonine Induces Glioblastoma Apoptosis via Inhibition of DNA Damage Repair.

Authors:  Yuan Li; Yunli Zhao; Xia Zhou; Wei Ni; Zhi Dai; Dong Yang; Junjun Hao; Lin Luo; Yaping Liu; Xiaodong Luo; Xudong Zhao
Journal:  Toxins (Basel)       Date:  2017-04-28       Impact factor: 4.546

  1 in total

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