Heike Luttmann-Gibson1, Stefanie Ebelt Sarnat, Helen H Suh, Brent A Coull, Joel Schwartz, Antonella Zanobetti, Diane R Gold. 1. From the Departments of Environmental Health (Drs Luttmann-Gibson, Sarnat, Suh, Schwartz, Zanobetti, and Gold) and Biostatistics (Dr Coull), Harvard School of Public Health, Boston, Mass; Department of Environmental and Occupational Health (Dr Sarnat), Emory University, Atlanta, Ga; Department of Health Sciences (Dr Suh), Northeastern University, Boston, Mass; and Channing Laboratory (Drs Schwartz and Gold), Harvard Medical School, Boston, Mass.
Abstract
OBJECTIVE: We examine whether ambient air pollution is associated with oxygen saturation in 32 elderly subjects in Steubenville, Ohio. METHODS: We used linear mixed models to examine the effects of fine particulate matter less than 2.5 μm (PM(2.5)), sulfate (SO(4)(-2)), elemental carbon, and gases on median oxygen saturation. RESULTS: An interquartile range increase of 13.4 μg/m in PM(2.5) on the previous day was associated with a decrease of -0.18% (95% confidence interval: -0.31 to -0.06) and a 5.1 μg/m(3) interquartile range increase in SO(4)(-2) on the previous day was associated with a decrease of -0.16% (95% confidence interval: -0.27 to -0.04) in oxygen saturation during the initial 5-minute rest period of the protocol. CONCLUSIONS: Increased exposure to air pollution, including the nontraffic pollutant SO(4)(-2) from industrial sources, led to changes in oxygen saturation that may reflect particle-induced pulmonary inflammatory or vascular responses.
OBJECTIVE: We examine whether ambient air pollution is associated with oxygen saturation in 32 elderly subjects in Steubenville, Ohio. METHODS: We used linear mixed models to examine the effects of fine particulate matter less than 2.5 μm (PM(2.5)), sulfate (SO(4)(-2)), elemental carbon, and gases on median oxygen saturation. RESULTS: An interquartile range increase of 13.4 μg/m in PM(2.5) on the previous day was associated with a decrease of -0.18% (95% confidence interval: -0.31 to -0.06) and a 5.1 μg/m(3) interquartile range increase in SO(4)(-2) on the previous day was associated with a decrease of -0.16% (95% confidence interval: -0.27 to -0.04) in oxygen saturation during the initial 5-minute rest period of the protocol. CONCLUSIONS: Increased exposure to air pollution, including the nontraffic pollutant SO(4)(-2) from industrial sources, led to changes in oxygen saturation that may reflect particle-induced pulmonary inflammatory or vascular responses.
Authors: Robert D Brook; Barry Franklin; Wayne Cascio; Yuling Hong; George Howard; Michael Lipsett; Russell Luepker; Murray Mittleman; Jonathan Samet; Sidney C Smith; Ira Tager Journal: Circulation Date: 2004-06-01 Impact factor: 29.690
Authors: Therese F Mar; Jane Q Koenig; Karen Jansen; Jeffrey Sullivan; Joel Kaufman; Carol A Trenga; Seyed H Siahpush; L-J Sally Liu; Lucas Neas Journal: Epidemiology Date: 2005-09 Impact factor: 4.822
Authors: J Schwartz; A Litonjua; H Suh; M Verrier; A Zanobetti; M Syring; B Nearing; R Verrier; P Stone; G MacCallum; F E Speizer; D R Gold Journal: Thorax Date: 2005-06 Impact factor: 9.139
Authors: Henry Gong; William S Linn; Kenneth W Clark; Karen R Anderson; Michael D Geller; Constantinos Sioutas Journal: Inhal Toxicol Date: 2005-03 Impact factor: 2.724
Authors: Dawn L DeMeo; Antonella Zanobetti; Augusto A Litonjua; Brent A Coull; Joel Schwartz; Diane R Gold Journal: Am J Respir Crit Care Med Date: 2004-05-13 Impact factor: 21.405
Authors: Iny Jhun; Jina Kim; Bennet Cho; Diane R Gold; Joel Schwartz; Brent A Coull; Antonella Zanobetti; Mary B Rice; Murray A Mittleman; Eric Garshick; Pantel Vokonas; Marie-Abele Bind; Elissa H Wilker; Francesca Dominici; Helen Suh; Petros Koutrakis Journal: J Air Waste Manag Assoc Date: 2019-08 Impact factor: 2.235
Authors: Oluwaseun A Akinseye; Stephen K Williams; Azizi Seixas; Seithikurippu R Pandi-Perumal; Julian Vallon; Ferdinand Zizi; Girardin Jean-Louis Journal: Int J Hypertens Date: 2015-03-02 Impact factor: 2.420
Authors: Stefanie Ebelt Sarnat; Andrea Winquist; James J Schauer; Jay R Turner; Jeremy A Sarnat Journal: Environ Health Perspect Date: 2015-01-09 Impact factor: 9.031
Authors: Martin Chaumont; Vanessa Tagliatti; El Mehdi Channan; Jean-Marie Colet; Alfred Bernard; Sofia Morra; Guillaume Deprez; Alain Van Muylem; Nadia Debbas; Thomas Schaefer; Vitalie Faoro; Philippe van de Borne Journal: Am J Physiol Lung Cell Mol Physiol Date: 2019-11-13 Impact factor: 5.464