| Literature DB >> 24447681 |
Lin Wu1, Jun Luo1, Yangmei Zhang1, Xiaobing Wang1, Lei Yang2, Lingyi Kong3.
Abstract
Seven new cassane diterpenoids (1-7), along with three known compounds (8-10), were isolated from the seed kernels of Caesalpinia bonduc. The structures were elucidated by extensive 1D and 2D NMR (HSQC, HMBC and ROESY) and mass (HRESIMS) spectroscopic data analyses. The structure and absolute configuration of compound 1 were confirmed by a single-crystal X-ray diffraction experiment. All isolates were tested for their cytotoxicity against HepG-2, MCF-7 and MG-63 cells, and 8-10 showed weak inhibitory activities.Entities:
Keywords: Caesalpinia bonduc; Cassane diterpenoids; Cytotoxicity
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Year: 2014 PMID： 24447681 DOI： 10.1016/j.fitote.2014.01.011
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882