| Literature DB >> 24445830 |
Stefan J W J Sanders1, Yuma A Bijleveld, Fleur Sinkeler, Elles M Kemper, Dasja Pajkrt, Marianne van de Wetering, Natasha K A van Eijkelenburg, Ron A A Mathôt.
Abstract
Vancomycin trough serum concentrations were below therapeutic range (8-15 mg/L) in 58% of 124 pediatric oncology patients receiving 60 mg/kg/d divided qid. Patients <6 and between 6 and 12 years had significantly lower trough concentrations than patients >12 years. A vancomycin dosage of 60 mg/kg/d is inadequate for pediatric oncology patients >12 years.Entities:
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Year: 2014 PMID： 24445830 DOI： 10.1097/INF.0000000000000268
Source DB: PubMed Journal: Pediatr Infect Dis J ISSN： 0891-3668 Impact factor: 2.129