Literature DB >> 24444596

The TWEAK-Fn14 pathway: a potent regulator of skeletal muscle biology in health and disease.

Marjan M Tajrishi1, Timothy S Zheng2, Linda C Burkly3, Ashok Kumar4.   

Abstract

TNF-like weak inducer of apoptosis (TWEAK), a TNF superfamily ligand, and its bona fide receptor, the TNF receptor superfamily member fibroblast growth factor-inducible 14 (Fn14), represent a pivotal axis for shaping both physiological and pathological tissue responses to acute or chronic injury and disease. In recent years significant advances have been made in delineating the prominent role of TWEAK-Fn14 dyad in regulating skeletal muscle mass and metabolism. Also emerging from the broad study of tissue injury in skeletal muscle and other organs is the role of the TWEAK-Fn14 pathway in promoting fibrosis. This review article highlights recent advancements toward understanding how the TWEAK-Fn14 pathway regulates the response to various skeletal muscle insults and, more broadly, engages multiple mechanisms to drive tissue fibrosis.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Fibrosis; NF-kappa B; Regeneration; Skeletal muscle atrophy; Tissue injury

Mesh：

Substances：

Year:  2013        PMID： 24444596      PMCID： PMC3999262          DOI： 10.1016/j.cytogfr.2013.12.004

Source DB:  PubMed          Journal:  Cytokine Growth Factor Rev        ISSN： 1359-6101            Impact factor:   7.638


  76 in total

Review 1.  TWEAK and TRAF6 regulate skeletal muscle atrophy.

Authors:  Ashok Kumar; Shephali Bhatnagar; Pradyut K Paul
Journal:  Curr Opin Clin Nutr Metab Care       Date:  2012-05       Impact factor: 4.294

2.  The E3 ubiquitin ligase TRAF6 intercedes in starvation-induced skeletal muscle atrophy through multiple mechanisms.

Authors:  Pradyut K Paul; Shephali Bhatnagar; Vivek Mishra; Sanjay Srivastava; Bryant G Darnay; Yongwon Choi; Ashok Kumar
Journal:  Mol Cell Biol       Date:  2012-01-30       Impact factor: 4.272

3.  TNF-related weak inducer of apoptosis (TWEAK) promotes kidney fibrosis and Ras-dependent proliferation of cultured renal fibroblast.

Authors:  Alvaro C Ucero; Alberto Benito-Martin; Isabel Fuentes-Calvo; Beatriz Santamaria; Julia Blanco; Jose M Lopez-Novoa; Marta Ruiz-Ortega; Jesus Egido; Linda C Burkly; Carlos Martinez-Salgado; Alberto Ortiz
Journal:  Biochim Biophys Acta       Date:  2013-06-06

4.  Proinflammatory effects of tumour necrosis factor-like weak inducer of apoptosis (TWEAK) on human gingival fibroblasts.

Authors:  Y Hosokawa; I Hosokawa; K Ozaki; H Nakae; T Matsuo
Journal:  Clin Exp Immunol       Date:  2006-12       Impact factor: 4.330

Review 5.  Signaling mechanisms in mammalian myoblast fusion.

Authors:  Sajedah M Hindi; Marjan M Tajrishi; Ashok Kumar
Journal:  Sci Signal       Date:  2013-04-23       Impact factor: 8.192

6.  RhoA signaling via serum response factor plays an obligatory role in myogenic differentiation.

Authors:  L Wei; W Zhou; J D Croissant; F E Johansen; R Prywes; A Balasubramanyam; R J Schwartz
Journal:  J Biol Chem       Date:  1998-11-13       Impact factor: 5.157

7.  Identification of Fn14/TWEAK receptor as a potential therapeutic target in esophageal adenocarcinoma.

Authors:  George S Watts; Nhan L Tran; Michael E Berens; Achyut K Bhattacharyya; Mark A Nelson; Elizabeth A Montgomery; Richard E Sampliner
Journal:  Int J Cancer       Date:  2007-11-15       Impact factor: 7.396

8.  Increased expression of atrogenes and TWEAK family members after severe burn injury in nonburned human skeletal muscle.

Authors:  Edward K Merritt; Anna Thalacker-Mercer; James M Cross; Samuel T Windham; Steven J Thomas; Marcas M Bamman
Journal:  J Burn Care Res       Date:  2013 Sep-Oct       Impact factor: 1.845

Review 9.  Therapy for fibrotic diseases: nearing the starting line.

Authors:  Scott L Friedman; Dean Sheppard; Jeremy S Duffield; Shelia Violette
Journal:  Sci Transl Med       Date:  2013-01-09       Impact factor: 17.956

Review 10.  Histone deacetylases.

Authors:  Paul A Marks; Thomas Miller; Victoria M Richon
Journal:  Curr Opin Pharmacol       Date:  2003-08       Impact factor: 5.547
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  20 in total

Review 1.  The emerging role of skeletal muscle oxidative metabolism as a biological target and cellular regulator of cancer-induced muscle wasting.

Authors:  James A Carson; Justin P Hardee; Brandon N VanderVeen
Journal:  Semin Cell Dev Biol       Date:  2015-12-01       Impact factor: 7.727

2.  The TWEAK-Fn14 dyad is involved in age-associated pathological changes in skeletal muscle.

Authors:  Marjan M Tajrishi; Shuichi Sato; Jonghyun Shin; Timothy S Zheng; Linda C Burkly; Ashok Kumar
Journal:  Biochem Biophys Res Commun       Date:  2014-03-26       Impact factor: 3.575

3.  Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits.

Authors:  Katherine E Bathgate; James R Bagley; Edward Jo; Robert J Talmadge; Irene S Tobias; Lee E Brown; Jared W Coburn; Jose A Arevalo; Nancy L Segal; Andrew J Galpin
Journal:  Eur J Appl Physiol       Date:  2018-07-14       Impact factor: 3.078

4.  Biomeasures and mechanistic modeling highlight PK/PD risks for a monoclonal antibody targeting Fn14 in kidney disease.

Authors:  Xiaoying Chen; Vahid Farrokhi; Pratap Singh; Mireia Fernandez Ocana; Jenil Patel; Lih-Ling Lin; Hendrik Neubert; Joanne Brodfuehrer
Journal:  MAbs       Date:  2017-11-30       Impact factor: 5.857

Review 5.  ER stress in skeletal muscle remodeling and myopathies.

Authors:  Dil Afroze; Ashok Kumar
Journal:  FEBS J       Date:  2017-12-29       Impact factor: 5.542

6.  TWEAK-Fn14 pathway activation after exercise in human skeletal muscle: insights from two exercise modes and a time course investigation.

Authors:  Ulrika Raue; Bozena Jemiolo; Yifan Yang; Scott Trappe
Journal:  J Appl Physiol (1985)       Date:  2014-12-24

7.  Elevated levels of TWEAK in skeletal muscle promote visceral obesity, insulin resistance, and metabolic dysfunction.

Authors:  Shuichi Sato; Yuji Ogura; Marjan M Tajrishi; Ashok Kumar
Journal:  FASEB J       Date:  2014-12-02       Impact factor: 5.191

8.  Effect of influenza vaccine on tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in older adults.

Authors:  Maryam Keshtkar-Jahromi; Min Ouyang; Marzieh Keshtkarjahromi; Samah Almed; Huifen Li; Jeremy D Walston; Rebeca Rios; Sean X Leng
Journal:  Vaccine       Date:  2018-03-13       Impact factor: 3.641

Review 9.  Disease-Induced Skeletal Muscle Atrophy and Fatigue.

Authors:  Scott K Powers; Gordon S Lynch; Kate T Murphy; Michael B Reid; Inge Zijdewind
Journal:  Med Sci Sports Exerc       Date:  2016-11       Impact factor: 5.411

10.  Heightened TWEAK-NF-κB signaling and inflammation-associated fibrosis in paralyzed muscles of men with chronic spinal cord injury.

Authors:  Ceren Yarar-Fisher; C Scott Bickel; Neil A Kelly; Michael J Stec; Samuel T Windham; Amie B McLain; Robert A Oster; Marcas M Bamman
Journal:  Am J Physiol Endocrinol Metab       Date:  2016-03-01       Impact factor: 4.310
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