Literature DB >> 24441290

Targeting proliferation of chronic lymphocytic leukemia (CLL) cells through KCa3.1 blockade.

E M Grössinger1, L Weiss2, S Zierler3, S Rebhandl2, P W Krenn2, E Hinterseer2, J Schmölzer4, D Asslaber2, S Hainzl5, D Neureiter6, A Egle2, J Piñón-Hofbauer2, T N Hartmann2, R Greil2, H H Kerschbaum7.   

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Year:  2014        PMID: 24441290     DOI: 10.1038/leu.2014.37

Source DB:  PubMed          Journal:  Leukemia        ISSN: 0887-6924            Impact factor:   11.528


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  15 in total

1.  B-cell chronic lymphocytic leukemia cells express a surface membrane phenotype of activated, antigen-experienced B lymphocytes.

Authors:  Rajendra N Damle; Fabio Ghiotto; Angelo Valetto; Emilia Albesiano; Franco Fais; Xiao-Jie Yan; Cristina P Sison; Steven L Allen; Jonathan Kolitz; Philip Schulman; Vincent P Vinciguerra; Petra Budde; Jurgen Frey; Kanti R Rai; Manlio Ferrarini; Nicholas Chiorazzi
Journal:  Blood       Date:  2002-06-01       Impact factor: 22.113

Review 2.  Nurture versus nature: the microenvironment in chronic lymphocytic leukemia.

Authors:  Jan A Burger
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2011

3.  In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells.

Authors:  Bradley T Messmer; Davorka Messmer; Steven L Allen; Jonathan E Kolitz; Prasad Kudalkar; Denise Cesar; Elizabeth J Murphy; Prasad Koduru; Manlio Ferrarini; Simona Zupo; Giovanna Cutrona; Rajendra N Damle; Tarun Wasil; Kanti R Rai; Marc K Hellerstein; Nicholas Chiorazzi
Journal:  J Clin Invest       Date:  2005-03       Impact factor: 14.808

4.  Mimicking the microenvironment in chronic lymphocytic leukaemia - where does the journey go?

Authors:  Daniela Asslaber; Eva M Grössinger; Tamara Girbl; Sebastian W Hofbauer; Alexander Egle; Lukas Weiss; Richard Greil; Tanja N Hartmann
Journal:  Br J Haematol       Date:  2012-12-04       Impact factor: 6.998

5.  Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production, and an immunogenic phenotype in chronic lymphocytic leukemia B cells.

Authors:  T Decker; F Schneller; T Sparwasser; T Tretter; G B Lipford; H Wagner; C Peschel
Journal:  Blood       Date:  2000-02-01       Impact factor: 22.113

6.  Therapeutic potential of KCa3.1 blockers: recent advances and promising trends.

Authors:  Heike Wulff; Neil A Castle
Journal:  Expert Rev Clin Pharmacol       Date:  2010-05       Impact factor: 5.045

7.  Functional up-regulation of HERG K+ channels in neoplastic hematopoietic cells.

Authors:  Garth A M Smith; Hing-Wo Tsui; Evan W Newell; Xinpo Jiang; Xiao-Ping Zhu; Florence W L Tsui; Lyanne C Schlichter
Journal:  J Biol Chem       Date:  2002-03-13       Impact factor: 5.157

Review 8.  Targeting ion channels in cancer: a novel frontier in antineoplastic therapy.

Authors:  A Arcangeli; O Crociani; E Lastraioli; A Masi; S Pillozzi; A Becchetti
Journal:  Curr Med Chem       Date:  2009       Impact factor: 4.530

Review 9.  Voltage-gated potassium channels as therapeutic targets.

Authors:  Heike Wulff; Neil A Castle; Luis A Pardo
Journal:  Nat Rev Drug Discov       Date:  2009-12       Impact factor: 84.694

Review 10.  The functional network of ion channels in T lymphocytes.

Authors:  Michael D Cahalan; K George Chandy
Journal:  Immunol Rev       Date:  2009-09       Impact factor: 12.988

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  12 in total

1.  Effects of ibandronate sodium, a nitrogen-containing bisphosphonate, on intermediate-conductance calcium-activated potassium channels in osteoclast precursor cells (RAW 264.7).

Authors:  Sheng-Nan Wu; Yan-Ming Huang; Yu-Kai Liao
Journal:  J Membr Biol       Date:  2014-11-02       Impact factor: 1.843

2.  KCNN4 Promotes the Stemness Potentials of Liver Cancer Stem Cells by Enhancing Glucose Metabolism.

Authors:  Jing Fan; Ruofei Tian; Xiangmin Yang; Hao Wang; Ying Shi; Xinyu Fan; Jiajia Zhang; Yatong Chen; Kun Zhang; Zhinan Chen; Ling Li
Journal:  Int J Mol Sci       Date:  2022-06-23       Impact factor: 6.208

3.  KCa3.1 (IK) modulates pancreatic cancer cell migration, invasion and proliferation: anomalous effects on TRAM-34.

Authors:  B Bonito; D R P Sauter; A Schwab; M B A Djamgoz; I Novak
Journal:  Pflugers Arch       Date:  2016-10-17       Impact factor: 3.657

Review 4.  Role of ion channels in regulating Ca²⁺ homeostasis during the interplay between immune and cancer cells.

Authors:  T Bose; A Cieślar-Pobuda; E Wiechec
Journal:  Cell Death Dis       Date:  2015-02-19       Impact factor: 8.469

5.  Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes.

Authors:  Aida Olivan-Viguera; Angel Luis Garcia-Otin; Javier Lozano-Gerona; Edgar Abarca-Lachen; Ana J Garcia-Malinis; Kirk L Hamilton; Yolanda Gilaberte; Esther Pueyo; Ralf Köhler
Journal:  PLoS One       Date:  2018-01-02       Impact factor: 3.240

Review 6.  Ion channels as therapeutic antibody targets.

Authors:  Catherine J Hutchings; Paul Colussi; Theodore G Clark
Journal:  MAbs       Date:  2018-12-10       Impact factor: 5.857

7.  Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling.

Authors:  Theresa Lowinus; Florian H Heidel; Tanima Bose; Subbaiah Chary Nimmagadda; Tina Schnöder; Clemens Cammann; Ingo Schmitz; Ulrike Seifert; Thomas Fischer; Burkhart Schraven; Ursula Bommhardt
Journal:  Cell Commun Signal       Date:  2019-01-16       Impact factor: 5.712

8.  KCa3.1 Channels Confer Radioresistance to Breast Cancer Cells.

Authors:  Corinna J Mohr; Dominic Gross; Efe C Sezgin; Friederike A Steudel; Peter Ruth; Stephan M Huber; Robert Lukowski
Journal:  Cancers (Basel)       Date:  2019-09-01       Impact factor: 6.639

9.  Complementary roles of KCa3.1 channels and β1-integrin during alveolar epithelial repair.

Authors:  Alban Girault; Jasmine Chebli; Anik Privé; Nguyen Thu Ngan Trinh; Emilie Maillé; Ryszard Grygorczyk; Emmanuelle Brochiero
Journal:  Respir Res       Date:  2015-09-04

10.  KCa3.1 Channel Modulators as Potential Therapeutic Compounds for Glioblastoma.

Authors:  Brandon M Brown; Brandon Pressley; Heike Wulff
Journal:  Curr Neuropharmacol       Date:  2018       Impact factor: 7.363

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