Literature DB >> 24440538

Optimum design of a moderator system based on dose calculation for an accelerator driven Boron Neutron Capture Therapy.

R Inoue1, F Hiraga2, Y Kiyanagi2.   

Abstract

An accelerator based BNCT has been desired because of its therapeutic convenience. However, optimal design of a neutron moderator system is still one of the issues. Therefore, detailed studies on materials consisting of the moderator system are necessary to obtain the optimal condition. In this study, the epithermal neutron flux and the RBE dose have been calculated as the indicators to look for optimal materials for the filter and the moderator. As a result, it was found that a combination of MgF2 moderator with Fe filter gave best performance, and the moderator system gave a dose ratio greater than 3 and an epithermal neutron flux over 1.0×10(9)cm(-2)s(-1).
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  BNCT; Dose; Epithermal neutron; Moderator system; Proton accelerator

Mesh:

Substances:

Year:  2013        PMID: 24440538     DOI: 10.1016/j.apradiso.2013.12.017

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  2 in total

1.  Evaluation of radioactivity in the bodies of mice induced by neutron exposure from an epi-thermal neutron source of an accelerator-based boron neutron capture therapy system.

Authors:  Satoshi Nakamura; Shoji Imamichi; Kazuyoshi Masumoto; Masashi Ito; Akihisa Wakita; Hiroyuki Okamoto; Shie Nishioka; Kotaro Iijima; Kazuma Kobayashi; Yoshihisa Abe; Hiroshi Igaki; Kazuyoshi Kurita; Teiji Nishio; Mitsuko Masutani; Jun Itami
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2017       Impact factor: 3.493

2.  Characterization of the relationship between neutron production and thermal load on a target material in an accelerator-based boron neutron capture therapy system employing a solid-state Li target.

Authors:  Satoshi Nakamura; Hiroshi Igaki; Masashi Ito; Hiroyuki Okamoto; Shie Nishioka; Kotaro Iijima; Hiroki Nakayama; Mihiro Takemori; Shoji Imamichi; Tairo Kashihara; Kana Takahashi; Koji Inaba; Kae Okuma; Naoya Murakami; Yoshihisa Abe; Yuko Nakayama; Mitsuko Masutani; Teiji Nishio; Jun Itami
Journal:  PLoS One       Date:  2019-11-22       Impact factor: 3.240

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.