Taiji Hasegawa1, Tetsuo Ueda2, Masahiro Okamoto2, Nahoko Ogata2. 1. Department of Ophthalmology, Nara Medical University, Nara, Japan. Electronic address: taijiha@naramed-u.ac.jp. 2. Department of Ophthalmology, Nara Medical University, Nara, Japan.
Abstract
PURPOSE: To determine whether a significant correlation exists between the presence of a bulge in the photoreceptor inner segment/outer segment (IS/OS) line and the best-corrected visual acuity (BCVA) in eyes with resolved macular edema associated with branch retinal vein occlusion (BRVO). DESIGN: Retrospective, observational case series. METHODS: We retrospectively reviewed the medical records of patients who had a complete resolution of macular edema and had an intact IS/OS line in the central fovea in the spectral-domain optical coherence tomographic (SDOCT) images. Thirty-one eyes with macular edema associated with BRVO (BRVO group) and 31 unaffected fellow eyes (control group) of 31 patients were evaluated. In normal eyes, the intact IS/OS line determined by SDOCT has a bulge at the central fovea, called the foveal bulge. The eyes in the BRVO group were classified by the presence or absence of foveal bulge, and the characteristics of the 2 groups were compared. RESULTS: A foveal bulge was present in 7 of 31 eyes in the BRVO group. The incidence of a foveal bulge was significantly lower in the BRVO group (22.6%) than in the control group (100%; P < .0001). All 7 eyes with foveal bulge had a decimal BCVA of ≥1.0 at the final visit. The incidence of a foveal bulge was significantly higher in eyes with BCVA of ≥1.0 (77.8%) than in the eyes with BCVA of <1.0 (0%; P < .0001). CONCLUSIONS: The foveal bulge is a good marker of the functional properties of the fovea in eyes with resolved macular edema associated with BRVO.
PURPOSE: To determine whether a significant correlation exists between the presence of a bulge in the photoreceptor inner segment/outer segment (IS/OS) line and the best-corrected visual acuity (BCVA) in eyes with resolved macular edema associated with branch retinal vein occlusion (BRVO). DESIGN: Retrospective, observational case series. METHODS: We retrospectively reviewed the medical records of patients who had a complete resolution of macular edema and had an intact IS/OS line in the central fovea in the spectral-domain optical coherence tomographic (SDOCT) images. Thirty-one eyes with macular edema associated with BRVO (BRVO group) and 31 unaffected fellow eyes (control group) of 31 patients were evaluated. In normal eyes, the intact IS/OS line determined by SDOCT has a bulge at the central fovea, called the foveal bulge. The eyes in the BRVO group were classified by the presence or absence of foveal bulge, and the characteristics of the 2 groups were compared. RESULTS: A foveal bulge was present in 7 of 31 eyes in the BRVO group. The incidence of a foveal bulge was significantly lower in the BRVO group (22.6%) than in the control group (100%; P < .0001). All 7 eyes with foveal bulge had a decimal BCVA of ≥1.0 at the final visit. The incidence of a foveal bulge was significantly higher in eyes with BCVA of ≥1.0 (77.8%) than in the eyes with BCVA of <1.0 (0%; P < .0001). CONCLUSIONS: The foveal bulge is a good marker of the functional properties of the fovea in eyes with resolved macular edema associated with BRVO.
Authors: Zhuo Li; Yanyan Peng; Robert B Hufnagel; Yueh-Chiang Hu; Chuntao Zhao; Luis F Queme; Zaza Khuchua; Ashley M Driver; Fei Dong; Q Richard Lu; Diana M Lindquist; Michael P Jankowski; Rolf W Stottmann; Winston W Y Kao; Taosheng Huang Journal: Hum Mol Genet Date: 2017-10-01 Impact factor: 6.150