Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Tumor antigenicity revealed.

Literature DB >> 24439426

Tumor antigenicity revealed.

Abstract

The extent to which mutated peptide antigens encoded by somatic mutations contribute to tumor antigenicity in human cancer patients has been unclear. Two recent studies using tumor exome sequencing to predict candidate mutated antigens provide insight into this question.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2014 PMID： 24439426 PMCID： PMC3932747 DOI： 10.1016/j.it.2014.01.001

Source DB: PubMed Journal: Trends Immunol ISSN： 1471-4906 Impact factor: 16.687

9 in total

Review 1. Database of T cell-defined human tumor antigens: the 2013 update.

Authors: Nathalie Vigneron; Vincent Stroobant; Benoît J Van den Eynde; Pierre van der Bruggen
Journal: Cancer Immun Date: 2013-07-15

2. Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy.

Authors: Steven A Rosenberg; James C Yang; Richard M Sherry; Udai S Kammula; Marybeth S Hughes; Giao Q Phan; Deborah E Citrin; Nicholas P Restifo; Paul F Robbins; John R Wunderlich; Kathleen E Morton; Carolyn M Laurencot; Seth M Steinberg; Donald E White; Mark E Dudley
Journal: Clin Cancer Res Date: 2011-04-15 Impact factor: 12.531

3. Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers.

Authors: Sine Reker Hadrup; Arnold H Bakker; Chengyi J Shu; Rikke S Andersen; Jerre van Veluw; Pleun Hombrink; Emilie Castermans; Per Thor Straten; Christian Blank; John B Haanen; Mirjam H Heemskerk; Ton N Schumacher
Journal: Nat Methods Date: 2009-06-21 Impact factor: 28.547

4. Improved survival with ipilimumab in patients with metastatic melanoma.

Authors: F Stephen Hodi; Steven J O'Day; David F McDermott; Robert W Weber; Jeffrey A Sosman; John B Haanen; Rene Gonzalez; Caroline Robert; Dirk Schadendorf; Jessica C Hassel; Wallace Akerley; Alfons J M van den Eertwegh; Jose Lutzky; Paul Lorigan; Julia M Vaubel; Gerald P Linette; David Hogg; Christian H Ottensmeier; Celeste Lebbé; Christian Peschel; Ian Quirt; Joseph I Clark; Jedd D Wolchok; Jeffrey S Weber; Jason Tian; Michael J Yellin; Geoffrey M Nichol; Axel Hoos; Walter J Urba
Journal: N Engl J Med Date: 2010-06-05 Impact factor: 91.245

Review 5. Adoptive immunotherapy for cancer: harnessing the T cell response.

Authors: Nicholas P Restifo; Mark E Dudley; Steven A Rosenberg
Journal: Nat Rev Immunol Date: 2012-03-22 Impact factor: 53.106

6. Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma.

Authors: Nienke van Rooij; Marit M van Buuren; Daisy Philips; Arno Velds; Mireille Toebes; Bianca Heemskerk; Laura J A van Dijk; Sam Behjati; Henk Hilkmann; Dris El Atmioui; Marja Nieuwland; Michael R Stratton; Ron M Kerkhoven; Can Kesmir; John B Haanen; Pia Kvistborg; Ton N Schumacher
Journal: J Clin Oncol Date: 2013-09-16 Impact factor: 44.544

Review 7. Cancer genome landscapes.

Authors: Bert Vogelstein; Nickolas Papadopoulos; Victor E Velculescu; Shibin Zhou; Luis A Diaz; Kenneth W Kinzler
Journal: Science Date: 2013-03-29 Impact factor: 47.728

8. Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens.

Authors: A Y Huang; P Golumbek; M Ahmadzadeh; E Jaffee; D Pardoll; H Levitsky
Journal: Science Date: 1994-05-13 Impact factor: 47.728

9. Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells.

Authors: Paul F Robbins; Yong-Chen Lu; Mona El-Gamil; Yong F Li; Colin Gross; Jared Gartner; Jimmy C Lin; Jamie K Teer; Paul Cliften; Eric Tycksen; Yardena Samuels; Steven A Rosenberg
Journal: Nat Med Date: 2013-05-05 Impact factor: 53.440