Sang Soo Kim1, Jong Chul Won2, Hyuk Sang Kwon3, Chong Hwa Kim4, Ji Hyun Lee5, Tae Sun Park6, Kyung Soo Ko7, Bong Yun Cha3. 1. Department of Internal Medicine, Pusan National University Hospital, Busan, South Korea. 2. Department of Internal Medicine, Cardiovascular and Metabolic Disease Centre, College of Medicine, Inje University, Seoul, South Korea. 3. Department of Internal Medicine, College of Medicine, the Catholic University of Korea, Seoul, South Korea. 4. Department of Internal Medicine, Sejong General Hospital, Bucheon, South Korea. 5. Department of Internal Medicine, School of Medicine, Catholic University of Daegu, Daegu, South Korea. 6. Department of Internal Medicine, Chonbuk National University Medical School, Jeonju, South Korea. 7. Department of Internal Medicine, Cardiovascular and Metabolic Disease Centre, College of Medicine, Inje University, Seoul, South Korea. Electronic address: kskomd@paik.ac.kr.
Abstract
AIMS: To determine the prevalence and risk factors for painful diabetic peripheral neuropathy (PDPN) and evaluate sleep impairment and quality of life in patients with PDPN. METHODS: Data from the Korean Diabetes Association Neuropathy Study Group were used to evaluate 3999 patients with type 2 diabetes. PDPN was diagnosed using visual analogue scales (VAS) and medical history. The patients were asked to answer the Brief Pain Inventory-Short Form (BPI-SF), Medical Outcomes Study Sleep (MOS-Sleep) Scale, EuroQol (EQ-5D), and VAS. RESULTS: Among the patients with diabetic peripheral neuropathy (n=1338), 577 (43.1%) were diagnosed with PDPN (14.4% of all patients with type 2 diabetes). PDPN was independently associated with age, female gender, fasting plasma glucose, hypertension, and previous cerebrovascular events. All pain severity and interference measures were higher in patients with PDPN than in non-PDPN patients, and patients with PDPN reported more impaired sleep and lower EQ-5D and VAS scores. CONCLUSIONS: The prevalence of PDPN in Koreans was comparable to that in Western populations. PDPN may impair sleep and quality of life compared with non-PDPN, and physicians should carefully consider pain symptoms in patients with diabetic peripheral neuropathy.
AIMS: To determine the prevalence and risk factors for painful diabetic peripheral neuropathy (PDPN) and evaluate sleep impairment and quality of life in patients with PDPN. METHODS: Data from the Korean Diabetes Association Neuropathy Study Group were used to evaluate 3999 patients with type 2 diabetes. PDPN was diagnosed using visual analogue scales (VAS) and medical history. The patients were asked to answer the Brief Pain Inventory-Short Form (BPI-SF), Medical Outcomes Study Sleep (MOS-Sleep) Scale, EuroQol (EQ-5D), and VAS. RESULTS: Among the patients with diabetic peripheral neuropathy (n=1338), 577 (43.1%) were diagnosed with PDPN (14.4% of all patients with type 2 diabetes). PDPN was independently associated with age, female gender, fasting plasma glucose, hypertension, and previous cerebrovascular events. All pain severity and interference measures were higher in patients with PDPN than in non-PDPN patients, and patients with PDPN reported more impaired sleep and lower EQ-5D and VAS scores. CONCLUSIONS: The prevalence of PDPN in Koreans was comparable to that in Western populations. PDPN may impair sleep and quality of life compared with non-PDPN, and physicians should carefully consider pain symptoms in patients with diabetic peripheral neuropathy.
Authors: Brian Callaghan; Kevin Kerber; Kenneth M Langa; Mousumi Banerjee; Ann Rodgers; Ryan McCammon; James Burke; Eva Feldman Journal: Neurology Date: 2015-05-27 Impact factor: 9.910