| Literature DB >> 2443777 |
V Faber1, A G Dalgleish, A Newell, M Malkovsky.
Abstract
A 58-year-old man with AIDS improved clinically after the introduction of fusidic acid, 500 mg three times a day orally, to his therapeutic regimen. Fusidic acid may have had a direct effect against HIV. Fusidic acid has anti-HIV activity in vitro at levels readily attainable in vivo. The drug does not appear to be a reverse transcriptase inhibitor and its mode of action against HIV is unknown. Fusidic acid can be given orally and has few side-effects. These results justify fuller evaluation of fusidic acid as therapy against AIDS and HIV infection.Entities:
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Year: 1987 PMID： 2443777 DOI： 10.1016/s0140-6736(87)91016-6
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321