Literature DB >> 24435599

Appropriateness of testing for serious bacterial infection in children hospitalized with bronchiolitis.

Jamie Librizzi1, Russell McCulloh, Kristin Koehn, Brian Alverson.   

Abstract

OBJECTIVE: The goal of this study was to evaluate provider practice patterns for evaluation of serious bacterial infection (SBI) in patients hospitalized with bronchiolitis and to assess the association of SBI testing with length of stay and antibiotic use.
DESIGN: This was a retrospective chart review of hospitalized patients <24 months of age with a discharge diagnosis of bronchiolitis from 2 separate study sites during 2004 to 2008. Patient characteristics, laboratory testing, antibiotic use, and clinical outcomes were assessed in relation to SBI testing.
RESULTS: A total of 1233 charts met inclusion criteria. The incidence of urinary tract infections in patients who underwent urine testing was 2.3%. Of the 367 patients undergoing blood culture testing, all 13 positive-result blood cultures were contaminated specimens. There were no cases of meningitis. In total, 64.5% of patients tested for SBI had a blood culture obtained, 45.0% had an urinalysis or urine culture, and 16.3% had a cerebral spinal fluid culture obtained. Of those patients who underwent SBI testing, 53.8% received antibiotics versus 19.1% who did not (P < .0001). Length of stay for patients undergoing SBI testing was 3.4 days versus 2.3 days for those without SBI testing (P < .0001). There was no significant difference in readmission rates.
CONCLUSIONS: SBI is uncommon in children hospitalized for bronchiolitis, and urinary tract infection is the most common diagnosis. In the evaluation of SBI in bronchiolitis, providers more frequently obtain blood cultures than urinalysis and/or urine cultures. Evaluation for SBI is associated with increased antibiotic use and increased LOS.

Entities:  

Keywords:  bacteremia; bacterial infections; bronchiolitis; meningitis; urinary tract infection

Mesh:

Year:  2014        PMID: 24435599     DOI: 10.1542/hpeds.2013-0073

Source DB:  PubMed          Journal:  Hosp Pediatr        ISSN: 2154-1671


  6 in total

1.  Bronchiolitis: Comparative Study between Respiratory Synctial Virus (RSV) and Non RSV Aetiology.

Authors:  Anirban Mandal; Amitabh Singh; Puneet Kaur Sahi; Bhavika Rishi
Journal:  J Clin Diagn Res       Date:  2017-02-01

2.  Bronchiolitis clinical practice guidelines implementation: surveillance study of hospitalized children in Jordan.

Authors:  Samah Awad; Rawan Hatim; Yousef Khader; Mohammad Alyahya; Nada Harik; Ahmad Rawashdeh; Walaa Qudah; Ruba Khasawneh; Wail Hayajneh; Dawood Yusef
Journal:  Multidiscip Respir Med       Date:  2020-10-09

3.  Association of Diagnostic Criteria With Urinary Tract Infection Prevalence in Bronchiolitis: A Systematic Review and Meta-analysis.

Authors:  Corrie E McDaniel; Shawn Ralston; Brian Lucas; Alan R Schroeder
Journal:  JAMA Pediatr       Date:  2019-03-01       Impact factor: 16.193

Review 4.  Viral bronchiolitis.

Authors:  Todd A Florin; Amy C Plint; Joseph J Zorc
Journal:  Lancet       Date:  2016-08-20       Impact factor: 79.321

5.  Prevalence of Bandemia in Respiratory Viral Infections: A Pediatric Emergency Room Experience.

Authors:  Estela Noyola; Asif Noor; Nicole Sweeney; Joshua Chan; Rahul Ramesh; Rose Calixte; Leonard R Krilov
Journal:  Front Pediatr       Date:  2020-12-29       Impact factor: 3.418

Review 6.  The contributions of allergic sensitization and respiratory pathogens to asthma inception.

Authors:  Daniel J Jackson; James E Gern; Robert F Lemanske
Journal:  J Allergy Clin Immunol       Date:  2016-03       Impact factor: 10.793

  6 in total

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