Literature DB >> 24435247

Genitourinary symptoms and their effects on quality of life in women with uterine myomas.

Murat Ekin1, Huseyin Cengiz, Emine Öztürk, Cihan Kaya, Levent Yasar, Kadir Savan.   

Abstract

INTRODUCTION AND HYPOTHESIS: This study was designed to determine the presence of genitourinary symptoms and their effects on quality of life (QOL) in women with uterine myomas.
METHODS: A total of 145 women with ultrasonography (US) diagnosis of anterior myoma were divided into two groups according to myoma size: (1) those ≤5 cm (n = 75), and (2) those >5 cm (n = 70). The control group comprised previously matched 94 women with a normal-appearing uterus on US. Study participants answered the Urogenital Distress Inventory (UDI-6) and the Incontinence Impact Questionnaire (IIQ-7). Pelvic examination was performed, and urinary symptoms were recorded. The chi-square test and Fischer's exact test were used to compare qualitative data. The Kruskal-Wallis test and Dunn's test were used to compare groups. Statistical significance was set at P <0.05.
RESULTS: The frequency of genitourinary symptoms was significantly higher in women with myomas, including stress urinary incontinence (SUI), urgency, frequency, urge urinary incontinence (UUI), and dyspareunia. SUI and mixed urinary incontinence (MUI) were the most common symptoms associated with myoma size. Total UDI-6 scores were significantly higher in women with myomas than in control patients (P < 0.0001). UDI scores associated with UI and obstructive symptoms were higher in women with myomas >5 cm than in other women. IIQ scores regarding physical activity, travel, and emotional health were significantly higher in women with myomas >5 cm than in other women (P < 0.001).
CONCLUSIONS: Urinary tract dysfunction is associated with anterior myomas, increasing in association with myoma size, and significantly affects QOL.

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Mesh:

Year:  2014        PMID: 24435247     DOI: 10.1007/s00192-013-2295-4

Source DB:  PubMed          Journal:  Int Urogynecol J        ISSN: 0937-3462            Impact factor:   2.894


  13 in total

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Authors:  Anca D Dragomir; Jane C Schroeder; AnnaMarie Connolly; Larry L Kupper; Deborah S Cousins; Andrew F Olshan; Donna D Baird
Journal:  J Womens Health (Larchmt)       Date:  2010-02       Impact factor: 2.681

9.  The Ontario Uterine Fibroid Embolization Trial. Part 2. Uterine fibroid reduction and symptom relief after uterine artery embolization for fibroids.

Authors:  Gaylene Pron; John Bennett; Andrew Common; Jane Wall; Murray Asch; Kenneth Sniderman
Journal:  Fertil Steril       Date:  2003-01       Impact factor: 7.329

10.  Genitourinary symptoms in patients with adenomyosis.

Authors:  Murat Ekin; Hüseyin Cengiz; Emine Öztürk; Cihan Kaya; Levent Yaşar
Journal:  Int Urogynecol J       Date:  2012-08-02       Impact factor: 2.894

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  2 in total

1.  G-protein-coupled estrogen receptor-30 gene polymorphisms are associated with uterine leiomyoma risk.

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2.  Therapeutic Outcome of MR-Guided High-Intensity Focused Ultrasound (MR-HIFU) in Solitary versus Multiple Uterine Fibroids.

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