Literature DB >> 2443430

Palliative laser therapy for malignant dysphagia.

N Krasner1, H Barr, C Skidmore, A I Morris.   

Abstract

Seventy six patients with dysphagia caused by malignant tumours of the oesophagus or gastric cardia have been treated using the Neodymium Yttrium Aluminium Garnet (NdYag) laser. The laser was set to deliver 80-100 watts of power for 0.5-1 second pulses. To obtain improvement, patients on average needed four treatment sessions with a mean energy per treatment of 3586 joules. Follow up endoscopy and laser treatment was at four week intervals, unless the clinical or endoscopic results indicated otherwise. The immediate result was to allow 32% of patients to swallow anything they liked, a further 54% were able to take most solids and 9% were improved, or maintained on liquids only. The mortality of laser recanalisation and associated treatment was 5%. The improvement in swallowing was maintained until death in all but 15% of these patients, some of the 15% needed intubation to allow adequate swallowing. Endoscopic, or surgical intubation was required immediately in five patients after an initial laser course failed to provide improvement. The mean survival of the whole group was 19 weeks (range one to 112 weeks).

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Year:  1987        PMID: 2443430      PMCID: PMC1433091          DOI: 10.1136/gut.28.7.792

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  23 in total

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Authors:  J N Leverment; D M Milne
Journal:  Br J Surg       Date:  1974-09       Impact factor: 6.939

2.  Multiple intestinal perforation due to Celestin tube.

Authors:  J F Shaw; G B Coombes
Journal:  Br J Surg       Date:  1979-11       Impact factor: 6.939

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Authors:  A G Pfleiderer; P Goodall; G K Holmes
Journal:  Br J Surg       Date:  1982-06       Impact factor: 6.939

4.  Palliative treatment of obstructing esophagogastric malignancy by endoscopic positioning of a plastic prosthesis.

Authors:  F C den Hartog Jager; J F Bartelsman; G N Tytgat
Journal:  Gastroenterology       Date:  1979-11       Impact factor: 22.682

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Authors:  Y K Wu; P T Chen; J P Fang; S S Lin
Journal:  Am J Surg       Date:  1980-06       Impact factor: 2.565

Review 6.  Oesophageal squamous cell carcinoma: I. A critical review of surgery.

Authors:  R Earlam; J R Cunha-Melo
Journal:  Br J Surg       Date:  1980-06       Impact factor: 6.939

Review 7.  Oesophogeal squamous cell carcinoms: II. A critical view of radiotherapy.

Authors:  R Earlam; J R Cunha-Melo
Journal:  Br J Surg       Date:  1980-07       Impact factor: 6.939

8.  A study of the quality and duration of survival following resection, endoscopic intubation and surgical intubation in oesophageal carcinoma.

Authors:  A Watson
Journal:  Br J Surg       Date:  1982-10       Impact factor: 6.939

9.  Palliative intubation of oesophagogastric neoplasms at fibreoptic endoscopy.

Authors:  A L Ogilvie; M W Dronfield; R Ferguson; M Atkinson
Journal:  Gut       Date:  1982-12       Impact factor: 23.059

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Authors:  M Atkinson; R Ferguson; G C Parker
Journal:  Gut       Date:  1978-07       Impact factor: 23.059

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  21 in total

1.  Guidelines for the management of oesophageal and gastric cancer.

Authors:  W H Allum; S M Griffin; A Watson; D Colin-Jones
Journal:  Gut       Date:  2002-06       Impact factor: 23.059

2.  Is the endoscopic view too narrow?

Authors:  T J Neal; N Krasner
Journal:  J Med Ethics       Date:  1992-12       Impact factor: 2.903

3.  Palliative bipolar electrocoagulation treatment of malignant gastroesophageal strictures.

Authors:  M Conio; L Bonelli; H Martines; F Munizzi; H Aste
Journal:  Surg Endosc       Date:  1990       Impact factor: 4.584

4.  Palliation of oesophageal cancer--endoscopic intubation and laser therapy.

Authors:  J D Urschel; J S Cockburn; A V Foote
Journal:  Postgrad Med J       Date:  1991-05       Impact factor: 2.401

5.  Palliation of malignant dysphagia: surgery, radiotherapy, laser, intubation alone or in combination?

Authors:  S G Bown
Journal:  Gut       Date:  1991-08       Impact factor: 23.059

6.  Photodynamic therapy of esophageal carcinoma.

Authors:  T Okunaka; H Kato; C Conaka; H Yamamoto; A Bonaminio; M L Eckhauser
Journal:  Surg Endosc       Date:  1990       Impact factor: 4.584

7.  Laser and brachytherapy in the palliation of adenocarcinoma of the oesophagus and cardia.

Authors:  G M Spencer; S M Thorpe; I R Sargeant; G M Blackman; J Solano; J S Tobias; S G Bown
Journal:  Gut       Date:  1996-11       Impact factor: 23.059

8.  A randomized comparison of dilatation alone versus dilatation plus laser in patients receiving chemotherapy and external beam radiation for esophageal carcinoma.

Authors:  B S Anand; Z A Saeed; P A Michaletz; C B Winchester; M A Doherty; J H Liem; D Y Graham
Journal:  Dig Dis Sci       Date:  1998-10       Impact factor: 3.199

9.  Palliation of malignant dysphagia using the Nd:YAG laser.

Authors:  R Carter; J S Smith; J R Anderson
Journal:  World J Surg       Date:  1993 Sep-Oct       Impact factor: 3.352

10.  Palliative removal of a giant polypoid 'carcinosarcoma' of the oesophagus by YAG laser photocoagulation of the tumour stalk.

Authors:  D Richardson; J I Wyatt; K J Miloszewski
Journal:  Gut       Date:  1992-08       Impact factor: 23.059

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