Makoto Ishitobi1, Masao Kawatani2, Mizuki Asano3, Hirotaka Kosaka4, Takashi Goto5, Michio Hiratani6, Yuji Wada7. 1. Department of Child and Adolescent Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, Japan; Department of Neuropsychiatry, University of Fukui, Japan. Electronic address: mak1977019@yahoo.co.jp. 2. Department of Pediatrics, University of Fukui, Japan. Electronic address: kawatani@u-fukui.ac.jp. 3. Department of Neuropsychiatry, University of Fukui, Japan. Electronic address: morio@u-fukui.ac.jp. 4. Research Center for Child Mental Development, University of Fukui, Japan. Electronic address: hirotaka@u-fukui.ac.jp. 5. Department of Neuropsychiatry, University of Fukui, Japan. Electronic address: gotot@u-fukui.ac.jp. 6. Hiratani Child Development Clinic, Fukui, Japan. Electronic address: m-hiratani@hiratani-c.jp. 7. Department of Neuropsychiatry, University of Fukui, Japan. Electronic address: waday@u-fukui.ac.jp.
Abstract
BACKGROUND: Bipolar disorder (BD) has been linked with the manifestation of catatonia in subjects with autism spectrum disorders (ASD). Idiopathic basal ganglia calcification (IBGC) is characterized by movement disorders and various neuropsychiatric disturbances including mood disorder. CASE: We present a patient with ASD and IBGC who developed catatonia presenting with prominent dystonic feature caused by comorbid BD, which was treated effectively with quetiapine. CONCLUSION: In addition to considering the possibility of neurodegenerative disease, careful psychiatric interventions are important to avoid overlooking treatable catatonia associated with BD in cases of ASD presenting with both prominent dystonic features and apparent fluctuation of the mood state.
BACKGROUND:Bipolar disorder (BD) has been linked with the manifestation of catatonia in subjects with autism spectrum disorders (ASD). Idiopathic basal ganglia calcification (IBGC) is characterized by movement disorders and various neuropsychiatric disturbances including mood disorder. CASE: We present a patient with ASD and IBGC who developed catatonia presenting with prominent dystonic feature caused by comorbid BD, which was treated effectively with quetiapine. CONCLUSION: In addition to considering the possibility of neurodegenerative disease, careful psychiatric interventions are important to avoid overlooking treatable catatonia associated with BD in cases of ASD presenting with both prominent dystonic features and apparent fluctuation of the mood state.