| Literature DB >> 24434172 |
E Takashita1, M Ejima, R Itoh, M Miura, A Ohnishi, H Nishimura, T Odagiri, M Tashiro.
Abstract
Six influenza A(H1N1)pdm09 viruses were detected in Sapporo, Japan, between November and December 2013. All six viruses possessed an H275Y substitution in the neuraminidase protein, which confers cross-resistance to oseltamivir and peramivir. No epidemiological link among the six cases could be identified; none of them had received neuraminidase inhibitors before specimen collection. The haemagglutinin and neuraminidase genes of the six viruses were closely related to one another, suggesting clonal spread of a single resistant virus.Entities:
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Year: 2014 PMID: 24434172 DOI: 10.2807/1560-7917.es2014.19.1.20666
Source DB: PubMed Journal: Euro Surveill ISSN: 1025-496X