Juan Cheng1, Hua-ye Ding, Yu-tang DU. 1. Department of Pathology, Dongzhimen Hospital, Beijing University of Chinese Medical Science, Beijing 100700, China. E-mail: chengjuan2002016@163.com.
Abstract
OBJECTIVE: To study the clinicopathologic features of granulomatous lobular mastitis and mammary duct ectasia. METHODS: The clinicopathologic data from August 2005 to May 2013 of 32 cases of granulomatous lobular mastitis and mammary duct ectasia were retrospectively reviewed. RESULTS: The age of patients ranged from 26 to 45 years. Two patients had no history of delivery. Fourteen patients had no history of lactation or lactational disorder in the lesional side. Most of the remaining patients had history of breast feeding. Gross examination showed that the lesions were poorly circumscribed and varied from 3 to 12 cm in greatest dimension. Tiny abscess cavities, ranging from 0.1 to 0.5 cm in diameter and containing light yellowish to greyish secretion, were demonstrated. Histologic examination showed granuloma formation and ductal dilatation. Eleven patients had received antibiotic treatment. Twelve cases were complicated by sinus formation related to skin incision and drainage. The duration of follow-up ranged from 5 to 90 months. Three cases showed ipsilateral recurrence and 3 cases had similar pathology in the contralateral breast. Four patients defaulted follow-up. CONCLUSIONS: Granulomatous lobular mastitis is associated with mammary duct ectasia. Accurate pathologic diagnosis is prudent for clinical management and control of local recurrence.
OBJECTIVE: To study the clinicopathologic features of granulomatous lobular mastitis and mammary duct ectasia. METHODS: The clinicopathologic data from August 2005 to May 2013 of 32 cases of granulomatous lobular mastitis and mammary duct ectasia were retrospectively reviewed. RESULTS: The age of patients ranged from 26 to 45 years. Two patients had no history of delivery. Fourteen patients had no history of lactation or lactational disorder in the lesional side. Most of the remaining patients had history of breast feeding. Gross examination showed that the lesions were poorly circumscribed and varied from 3 to 12 cm in greatest dimension. Tiny abscess cavities, ranging from 0.1 to 0.5 cm in diameter and containing light yellowish to greyish secretion, were demonstrated. Histologic examination showed granuloma formation and ductal dilatation. Eleven patients had received antibiotic treatment. Twelve cases were complicated by sinus formation related to skin incision and drainage. The duration of follow-up ranged from 5 to 90 months. Three cases showed ipsilateral recurrence and 3 cases had similar pathology in the contralateral breast. Four patients defaulted follow-up. CONCLUSIONS:Granulomatous lobular mastitis is associated with mammary duct ectasia. Accurate pathologic diagnosis is prudent for clinical management and control of local recurrence.
Authors: Ignacio Pinilla-Pagnon; Belén Pérez-Mies; María Eugenia Reguero; Marco-Tulio Martinez; Miguel Chiva; Silvia Pérez-Rodrigo; Odile Ajuria Illarramendi; Maria Eugenia Rioja Martin; Maria Vicenta Collado; Maria Concepción Sanchez; Juan Manuel Rosa-Rosa; José Palacios Journal: Virchows Arch Date: 2018-07-08 Impact factor: 4.064
Authors: Radjiv Goulabchand; Assia Hafidi; Philippe Van de Perre; Ingrid Millet; Alexandre Thibault Jacques Maria; Jacques Morel; Alain Le Quellec; Hélène Perrochia; Philippe Guilpain Journal: J Clin Med Date: 2020-03-30 Impact factor: 4.964