Literature DB >> 2443218

Developmental expression and regional distribution of the scrapie-associated protein mRNA in the rat central nervous system.

I Lieberburg1.   

Abstract

The scrapie associated protein (SAP) has been shown to be a normal brain protein of yet undefined function. This study demonstrates that rat brain SAP mRNA levels undergo a transcriptionally dependent increase during normal development. The interregional variation in the adult rat central nervous system (CNS) is roughly 10 fold, with highest levels in the basal ganglion/thalamus and lowest levels in the spinal cord.

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Year:  1987        PMID： 2443218     DOI： 10.1016/0006-8993(87)90465-3

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  7 in total

1.  Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain.

Authors:  W C Mobley; R L Neve; S B Prusiner; M P McKinley
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

2.  Localization of the mRNA for a chicken prion protein by in situ hybridization.

Authors:  D A Harris; P Lele; W D Snider
Journal:  Proc Natl Acad Sci U S A       Date:  1993-05-01       Impact factor: 11.205

3.  Proliferative arrest of neural cells induces prion protein synthesis, nanotube formation, and cell-to-cell contacts.

Authors:  Kohtaro Miyazawa; Kaitlin Emmerling; Laura Manuelidis
Journal:  J Cell Biochem       Date:  2010-09-01       Impact factor: 4.429

Review 4.  Inhibition of scrapie-associated PrP accumulation. Probing the role of glycosaminoglycans in amyloidogenesis.

Authors:  S A Priola; B Caughey
Journal:  Mol Neurobiol       Date:  1994 Apr-Jun       Impact factor: 5.590

5.  Embryonic activation and developmental expression of the murine prion protein gene.

Authors:  G Miele; A R Alejo Blanco; H Baybutt; S Horvat; J Manson; M Clinton
Journal:  Gene Expr       Date:  2003

6.  Reduced Expression of Prion Protein With Increased Interferon-β Fail to Limit Creutzfeldt-Jakob Disease Agent Replication in Differentiating Neuronal Cells.

Authors:  Gerard Aguilar; Nathan Pagano; Laura Manuelidis
Journal:  Front Physiol       Date:  2022-02-18       Impact factor: 4.566

Review 7.  Prions and related neurological diseases.

Authors:  M Pocchiari
Journal:  Mol Aspects Med       Date:  1994
  7 in total

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