Literature DB >> 24432087

Intramedullary rod fixation of fibrous dysplasia without use of bisphosphonates.

Greg Gaski1, Dane Hansen1, Leisel M Willis1, Gary D Bos2, John R Kean3.   

Abstract

PURPOSE: Controversy exists regarding approach to treatment of pediatric patients with fibrous dysplasia.
METHODS: We retrospectively reviewed medical records of seven patients who were treated at our institution for fibrous dysplasia by intramedullary rod fixation without bisphosphonate supplementation.
RESULTS: Seven patients with a total of ten fibrous dysplasia lesion sites surgically treated by intramedullary rod fixation were included. Of these ten lesion sites, eight demonstrated pathologic fracture at the time of fixation. Complete fracture healing was observed in all eight sites, with no incidence of recurrent pathologic fractures examined radiographically. There were no major infections or neurologic deficits, and lesions appeared to stabilize.
CONCLUSIONS: In this series, intramedullary rod fixation proved to be successful in treatment of acute pathologic fracture and incompletely healed fibrous dysplasia lesions. We observed partial resolution of fibrous dysplasia lesions at all ten sites without significant long-term complications. Following treatment, there were no refractures. LEVEL OF EVIDENCE: Level IV, case series.

Entities:  

Keywords:  Biphosphonates; Fibrous dyslplasia; Intramedullary fixations; Lesion; Pathologic fracture

Year:  2013        PMID: 24432087      PMCID: PMC3799931          DOI: 10.1007/s11832-013-0522-7

Source DB:  PubMed          Journal:  J Child Orthop        ISSN: 1863-2521            Impact factor:   1.548


  23 in total

1.  The natural history of fibrous dysplasia. An orthopaedic, pathological, and roentgenographic study.

Authors:  W H HARRIS; H R DUDLEY; R J BARRY
Journal:  J Bone Joint Surg Am       Date:  1962-03       Impact factor: 5.284

2.  [The prevention and treatment of skeletal deformities in fibrous dysplasia].

Authors:  F S Santori; M Manili; F Falez; U Mattioli
Journal:  Arch Putti Chir Organi Mov       Date:  1990

Review 3.  Fibrous dysplasia. Pathophysiology, evaluation, and treatment.

Authors:  Matthew R DiCaprio; William F Enneking
Journal:  J Bone Joint Surg Am       Date:  2005-08       Impact factor: 5.284

4.  Bisphosphonate treatment of bone fibrous dysplasia in McCune-Albright syndrome.

Authors:  Roberto Lala; Patrizia Matarazzo; Maria Andreo; Daniela Marzari; Jaele Bellone; Andrea Corrias; Carlo de Sanctis
Journal:  J Pediatr Endocrinol Metab       Date:  2006-05       Impact factor: 1.634

5.  Intramedullary rodding and bisphosphonate treatment of polyostotic fibrous dysplasia associated with the McCune-Albright syndrome.

Authors:  Mark O'Sullivan; Margaret Zacharin
Journal:  J Pediatr Orthop       Date:  2002 Mar-Apr       Impact factor: 2.324

6.  [Treatment of femoral fractures associated with fibrous dysplasia: a case report].

Authors:  Ozal Ozcan; Hakan Boya; Onder Baran; Hasan Havitçioğlu
Journal:  Acta Orthop Traumatol Turc       Date:  2002       Impact factor: 1.511

7.  Treatment of monostotic fibrous dysplasia with pamidronate.

Authors:  Marcin Kos; Klaudiusz Luczak; Jan Godzinski; Jan Klempous
Journal:  J Craniomaxillofac Surg       Date:  2004-02       Impact factor: 2.078

8.  Treatment of fibrous dysplasia of bone with intravenous pamidronate: long-term effectiveness and evaluation of predictors of response to treatment.

Authors:  R D Chapurlat; P Hugueny; P D Delmas; P J Meunier
Journal:  Bone       Date:  2004-07       Impact factor: 4.398

9.  Surgical treatment of fibrous dysplasia of bone in McCune-Albright syndrome.

Authors:  E Ippolito; R Caterini; P Farsetti; V Potenza
Journal:  J Pediatr Endocrinol Metab       Date:  2002       Impact factor: 1.634

Review 10.  Fibrous dysplasia.

Authors:  Eckhard Schoenau; Frank Rauch
Journal:  Horm Res       Date:  2002
View more
  2 in total

1.  Functional and radiological outcomes of a minimally invasive surgical approach to monostotic fibrous dysplasia.

Authors:  Mamer S Rosario; Katsuhiro Hayashi; Norio Yamamoto; Akihiko Takeuchi; Shinji Miwa; Yuta Taniguchi; Hiroyuki Tsuchiya
Journal:  World J Surg Oncol       Date:  2017-01-05       Impact factor: 2.754

2.  Treatment of diaphyseal pathological fractures in children with monostotic fibrous dysplasia using cortical strut allografts and internal plating: A retrospective clinical study.

Authors:  Peng Zhang; Liangqi Kang; Qimiao Hu; Chenjie Xia; Huan Yu; Lei Wang; Kejian Lian; Dasheng Lin
Journal:  Medicine (Baltimore)       Date:  2019-02       Impact factor: 1.817

  2 in total

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