Anita Soni1, Seeru Garg1, Rani Bangar1. 1. Department of Obstetrics and Gynecology, Dr. LH Hiranandani Hospital, Hillside Avenue, Hiranandani Gardens, Powai, Mumbai, 400076 Maharashtra India.
Abstract
OBJECTIVE: To assess the contraceptive efficacy, user acceptability, cycle control, and tolerability of a combined contraceptive vaginal ring for up to 13 cycles. MATERIALS AND METHODS: Healthy women coming to the OPD for contraceptive advice were enrolled in this one-year study. Each ring was used for three weeks followed by a one-week ring-free period. RESULTS: A total of 184 women started treatment forming the intent to treat population. Subjects were followed for 13 cycles. Compliance was good with 99 % of cycles in full compliance with specified criteria. In the intent to treat population, no pregnancies occurred giving a Pearl Index of 0. The mean incidence of withdrawal bleeding was 99 % in all cycles. There was 0.16 % incidence of intermenstrual bleeding and 2 % incidence of early withdrawal bleeding. The ring was well tolerated with a low incidence of adverse events. CONCLUSION: The ring is an effective contraceptive that is convenient, well tolerated with excellent cycle control, and highly acceptable to users.
OBJECTIVE: To assess the contraceptive efficacy, user acceptability, cycle control, and tolerability of a combined contraceptive vaginal ring for up to 13 cycles. MATERIALS AND METHODS: Healthy women coming to the OPD for contraceptive advice were enrolled in this one-year study. Each ring was used for three weeks followed by a one-week ring-free period. RESULTS: A total of 184 women started treatment forming the intent to treat population. Subjects were followed for 13 cycles. Compliance was good with 99 % of cycles in full compliance with specified criteria. In the intent to treat population, no pregnancies occurred giving a Pearl Index of 0. The mean incidence of withdrawal bleeding was 99 % in all cycles. There was 0.16 % incidence of intermenstrual bleeding and 2 % incidence of early withdrawal bleeding. The ring was well tolerated with a low incidence of adverse events. CONCLUSION: The ring is an effective contraceptive that is convenient, well tolerated with excellent cycle control, and highly acceptable to users.
Authors: Elena E Grodnitskaya; Olga R Grigoryan; Elena V Klinyshkova; Elena N Andreeva; Galina A Melnichenko; Ivan I Dedov Journal: Gynecol Endocrinol Date: 2010-09 Impact factor: 2.260
Authors: I Milsom; I Lete; A Bjertnaes; K Rokstad; I Lindh; C J Gruber; M H Birkhäuser; E Aubeny; T Knudsen; C Bastianelli Journal: Hum Reprod Date: 2006-06-08 Impact factor: 6.918
Authors: Sara E Vargas; Miriam M Midoun; Melissa Guillen; Melissa L Getz; Kristen Underhill; Caroline Kuo; Kate M Guthrie Journal: Perspect Sex Reprod Health Date: 2019-05-20
Authors: Kathleen Ridgeway; Elizabeth T Montgomery; Kevin Smith; Kristine Torjesen; Ariane van der Straten; Sharon L Achilles; Jennifer B Griffin Journal: Contraception Date: 2021-10-10 Impact factor: 3.051
Authors: Suchitra N Pandit; Anahita R Chauhan; Manjula Anagani; Sanjeeva Reddy; Ashish Birla; Subrat K Ray Journal: J Obstet Gynaecol India Date: 2014-05-15
Authors: Evelyne Kestelyn; Jennifer Ilo Van Nuil; Marie Michelle Umulisa; Grace Umutoni; Alice Uwingabire; Lambert Mwambarangwe; Mireille Uwineza; Stephen Agaba; Tania Crucitti; Janneke van de Wijgert; Thérèse Delvaux Journal: PLoS One Date: 2018-06-18 Impact factor: 3.240
Authors: Jennifer B Griffin; Kathleen Ridgeway; Elizabeth Montgomery; Kristine Torjesen; Rachel Clark; Jill Peterson; Rachel Baggaley; Ariane van der Straten Journal: PLoS One Date: 2019-11-08 Impact factor: 3.240
Authors: Danielle M Harris; Anita Dam; Kate Morrison; Chastain Mann; Ashley Jackson; Shannon M Bledsoe; Andrea Rowan; Kim Longfield Journal: Stud Fam Plann Date: 2022-08-03