Geeta Jain1, Urmila Palaria2, S K Jha3. 1. Department of O&G, Govt. Medical College, Haldwani, Rampur Road, Haldwani, Uttarakhand India. 2. Department of Anaesthesia, Govt. Medical College, Haldwani, Rampur Road, Haldwani, Uttarakhand India. 3. Department of PSM, Govt. Medical College, Haldwani, Rampur Road, Haldwani, Uttarakhand India.
Abstract
OBJECTIVE: To compare effectiveness of intravenous iron-sucrose versus oral ferrous fumarate in postpartum anemia. METHODS: In this study, 40 women with postpartum anemia with hemoglobin (Hb) less than 8 g/dl within 48 h postpartum were randomised into two groups. Group I consisted of 20 women who received 300-600 mg of intravenous iron-sucrose every alternate day for 3 days. Group II consisted of 20 women who were given 300 mg ferrous fumarate orally daily for 14 days. RESULTS: On day 14, the increase in mean Hb level in group I was 2.4 g/dl in comparison to 1.2 g/dl in group II. Women in group I had significantly higher mean Hb values on days 7 and 14 (p < 0.001) than women in group II. CONCLUSION: These results suggest that intravenous iron-sucrose increases the Hb level more rapidly than oral ferrous fumarate in postpartum anemia without any serious side effects.
RCT Entities:
OBJECTIVE: To compare effectiveness of intravenous iron-sucrose versus oral ferrous fumarate in postpartum anemia. METHODS: In this study, 40 women with postpartum anemia with hemoglobin (Hb) less than 8 g/dl within 48 h postpartum were randomised into two groups. Group I consisted of 20 women who received 300-600 mg of intravenous iron-sucrose every alternate day for 3 days. Group II consisted of 20 women who were given 300 mg ferrous fumarate orally daily for 14 days. RESULTS: On day 14, the increase in mean Hb level in group I was 2.4 g/dl in comparison to 1.2 g/dl in group II. Women in group I had significantly higher mean Hb values on days 7 and 14 (p < 0.001) than women in group II. CONCLUSION: These results suggest that intravenous iron-sucrose increases the Hb level more rapidly than oral ferrous fumarate in postpartum anemia without any serious side effects.
Authors: Pervez Sultan; Sohail Bampoe; Raj Shah; Nan Guo; Jaclyn Estes; Christopher Stave; Lawrence Tim Goodnough; Stephen Halpern; Alex James Butwick Journal: Am J Obstet Gynecol Date: 2018-12-19 Impact factor: 8.661
Authors: Akshay A Shah; Killian Donovan; Claire Seeley; Edward A Dickson; Antony J R Palmer; Carolyn Doree; Susan Brunskill; Jack Reid; Austin G Acheson; Anita Sugavanam; Edward Litton; Simon J Stanworth Journal: JAMA Netw Open Date: 2021-11-01