Literature DB >> 2442790

Activation of forebrain dopamine systems by phencyclidine and footshock stress: evidence for distinct mechanisms.

M B Bowers, M J Bannon, F J Hoffman.   

Abstract

Phencyclidine combined with footshock stress produced a greater increase in the homovanillic acid content of prefrontal cortex than either phencyclidine or footshock alone. Phencyclidine decreased both substance P and substance K in the ventral tegmental area. The results suggest that phencyclidine and footshock activate forebrain dopaminergic systems in part by separate mechanisms.

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Year:  1987        PMID： 2442790     DOI： 10.1007/bf02439600

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  15 in total

1.  LSD: effect on monoamine metabolites in rat prefrontal cortex.

Authors:  M B Bowers; L A Salomonsson
Journal:  Biochem Pharmacol       Date:  1982-12-15       Impact factor: 5.858

2.  Conditioned fear and startle magnitude: effects of different footshock or backshock intensities used in training.

Authors:  M Davis; D I Astrachan
Journal:  J Exp Psychol Anim Behav Process       Date:  1978-04

3.  Regional brain homovanillic acid following delta 9-tetrahydrocannabinol and cocaine.

Authors:  M B Bowers; F J Hoffman
Journal:  Brain Res       Date:  1986-02-26       Impact factor: 3.252

4.  Enhanced noradrenergic neuronal activity increases homovanillic acid levels in cerebrospinal fluid.

Authors:  H Scheinin
Journal:  J Neurochem       Date:  1986-09       Impact factor: 5.372

5.  Homovanillic acid in rat caudate and prefrontal cortex following phencyclidine and amphetamine.

Authors:  M B Bowers; F J Hoffman
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

6.  Tolerance to fluphenazine and supersensitivity to apomorphine in central dopaminergic systems after chronic fluphenazine decanoate treatment.

Authors:  S C Wheeler; R H Roth
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1980-06       Impact factor: 3.000

7.  Mesocortical dopamine neurons: rapid transmitter turnover compared to other brain catecholamine systems.

Authors:  M J Bannon; E B Bunney; R H Roth
Journal:  Brain Res       Date:  1981-08-10       Impact factor: 3.252

8.  Substance K and substance P differentially modulate mesolimbic and mesocortical systems.

Authors:  A Y Deutch; J E Maggio; M J Bannon; P W Kalivas; S Y Tam; M Goldstein; R H Roth
Journal:  Peptides       Date:  1985       Impact factor: 3.750

Review 9.  Pharmacology of mesocortical dopamine neurons.

Authors:  M J Bannon; R H Roth
Journal:  Pharmacol Rev       Date:  1983-03       Impact factor: 25.468

10.  Footshock and conditioned stress increase 3,4-dihydroxyphenylacetic acid (DOPAC) in the ventral tegmental area but not substantia nigra.

Authors:  A Y Deutch; S Y Tam; R H Roth
Journal:  Brain Res       Date:  1985-04-29       Impact factor: 3.252
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  1 in total

Review 1.  Management of the negative symptoms of schizophrenia: new treatment options.

Authors:  Hans-Jürgen Möller
Journal:  CNS Drugs       Date:  2003       Impact factor: 5.749
  1 in total

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